DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12343 and syf-2

DIOPT Version :9

Sequence 1:	NP_610617.1	Gene:	CG12343 / 36143	FlyBaseID:	FBgn0033556	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001379563.1	Gene:	syf-2 / 176003	WormBaseID:	WBGene00019402	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	101/222 - (45%)
Similarity:	154/222 - (69%)	Gaps:	2/222 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TAAEKLAERKARLLDLHKKRQEARTDNHQEVVAEDARKKLPKNWEARKRQAEWILADDKARAEAQ 70
            ::..|:.:...|..||||.||.||.:||::||.||.|.|||||.||:|.:.:|.:.:.:.|..|:
Worm    14 SSGSKMKDFNQRFRDLHKLRQRARKENHEQVVEEDRRSKLPKNHEAKKERDQWQVKELQDRKAAE 78

  Fly    71 AAGKDYERLKLLEVSAVDADRIEKKKKRKDNPDLGFSTYEAQTARQYNRLVKSMPARDLEKYERQ 135
            ..|.||||::.||:||...:::|:|:|||.|||.||::||..|.||:.||..::.. ||:.|::.
Worm    79 DKGLDYERVRSLEMSADVTEKLEQKRKRKKNPDQGFTSYEDMTLRQHTRLTAALDP-DLDSYKKM 142

  Fly   136 KEEL-GDAFYGGAHTTLHSRTKDTPGAINKMVTDLEQQIERRKKYSRRRIYNDDADVDFINERNS 199
            :|.: |:.||..|.|.:|.....|..|::|:..|:..|::||::|.|||:|:.||.:|:|||:|.
Worm   143 RECVGGEQFYPTADTLIHGNHYPTTAAMDKLTKDVHGQVKRREQYHRRRLYDPDAPIDYINEKNK 207

  Fly   200 KFNKKLDRFYSEHTAEIKQNLERGTAI 226
            |||||||::|.::|.:||.:|||||||
Worm   208 KFNKKLDKYYGKYTEDIKDDLERGTAI 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12343	NP_610617.1	SYF2	71..221	CDD:285444	66/150 (44%)
syf-2	NP_001379563.1	SYF2	79..229	CDD:400506	66/150 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158768
Domainoid	1	1.000	144	1.000	Domainoid score	I2862
eggNOG	1	0.900	-	-		E1_KOG2609
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5993
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2396
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55400
OrthoDB	1	1.010	-	-		D1565402at2759
OrthoFinder	1	1.000	-	-		FOG0004947
OrthoInspector	1	1.000	-	-		oto18704
orthoMCL	1	0.900	-	-		OOG6_103856
Panther	1	1.100	-	-	LDO	PTHR13264
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1436
SonicParanoid	1	1.000	-	-		X3486
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840