DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7222 and desi2

DIOPT Version :9

Sequence 1:	NP_001286295.1	Gene:	CG7222 / 36138	FlyBaseID:	FBgn0033551	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001003532.1	Gene:	desi2 / 445138	ZFINID:	ZDB-GENE-040801-39	Length:	196	Species:	Danio rerio

Alignment Length:	169	Identity:	111/169 - (65%)
Similarity:	144/169 - (85%)	Gaps:	5/169 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EPVILNVYDMYWINEYTTSIGLGVFHSGVEAFGTEFAYGGHPFPFTGVFEISPRDHDELGDQFQF 101
            |||||||||||||||:|:|:|:||||||:|.:|.||||||||:||:|:|||:|.|..|||:.|:|
Zfish     4 EPVILNVYDMYWINEFTSSLGIGVFHSGIEIYGREFAYGGHPYPFSGIFEITPGDATELGETFKF 68

  Fly   102 RQSIQIGCTDFTYEEVRRIVEELGNQFRGDRYHLMNNNCNHFSGSLTQILCGQEIPSWVNRLAHF 166
            :::|.:|.||||.|:|.|||||:|.:::|:.||||:.||||||.:|::||||:|||.||||||:|
Zfish    69 KEAIVLGSTDFTEEDVERIVEEMGKEYKGNAYHLMHKNCNHFSSALSEILCGREIPRWVNRLAYF 133

  Fly   167 SSCVPFLQRCLPKEWLTPNALQQSIT-----TIQEREDS 200
            ||||||||.|||||||||.|||.|::     .::|.||:
Zfish   134 SSCVPFLQSCLPKEWLTPAALQSSVSQELQGELEEAEDA 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7222	NP_001286295.1	Peptidase_C97	37..181	CDD:399119	99/143 (69%)
desi2	NP_001003532.1	Peptidase_C97	4..148	CDD:283538	99/143 (69%)
desi2	NP_001003532.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..196		3/14 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595901
Domainoid	1	1.000	233	1.000	Domainoid score	I2335
eggNOG	1	0.900	-	-		E1_KOG0324
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56741
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3167
OMA	1	1.010	-	-		QHG59072
OrthoDB	1	1.010	-	-		D1300278at2759
OrthoFinder	1	1.000	-	-		FOG0001883
OrthoInspector	1	1.000	-	-		otm26411
orthoMCL	1	0.900	-	-		OOG6_101256
Panther	1	1.100	-	-	LDO	PTHR12378
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R546
SonicParanoid	1	1.000	-	-		X1415
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800