Protein Alignment Amfr and HRD1

DIOPT Version :9

• Sequence 1: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Sequence 2: NP_014630.1
• Gene: HRD1 / 854149
• SGDID: S000005373
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 429
• Identity: 88/429 - (20%)
• Similarity: 169/429 - (39%)
• Gaps: 136/429 - (31%)

  Rat    82 LFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDK----FWNFIFYKFIFIFGVLNVQTV 142
            |.:::|:|:.     |:.:|:..::||.||:.|.:|:.::    ..|.:|...:|
Yeast    51 LSIFILLNST-----LLWQLLTKLLFGELRLIEHEHIFERLPFTIINTLFMSSLF---------- 100

  Rat   143 EEVVMWCLWFAGLVFLHLMV--QLCKDRFEYL--SFSPTTPMSS--HGRVLSLLIAMLLSCCGLA 201
            .|...:.:.|.||:.|:|.|  .:.|||.|.|  |.:.:|.|.:  ..|....|:.:.:....:.
Yeast   101 HERYFFTVAFFGLLLLYLKVFHWILKDRLEALLQSINDSTTMKTLIFSRFSFNLVLLAVVDYQII 165

  Rat   202 VVCCVTGYTH--------GMHTLAFMAAESLLVTVRTAHVILRYVIHLWDL-----------NH- 246
            ..|..:.||:        .::.:..|....||:.:  .::.|:..::.|:.           ||
Yeast   166 TRCISSIYTNQKSDIESTSLYLIQVMEFTMLLIDL--LNLFLQTCLNFWEFYRSQQSLSNENNHI 228

  Rat   247 -------EGTWEG-----------------------KGTYVY------YTDFVMELMLLSLDLMH 275
                   |.|.|.                       :|.::|      :|.|:...:.||:.:..
Yeast   229 VHGDPTDENTVESDQSQPVLNDDDDDDDDDRQFTGLEGKFMYEKAIDVFTRFLKTALHLSMLIPF 293

  Rat   276 HIHMLLFGN-IWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATAEEL--AVN 337
            .:.|:|..: :|   ..|.::.....|:     :|.|:...|      :......|.|:|  :.|
Yeast   294 RMPMMLLKDVVW---DILALYQSGTSLW-----KIWRNNKQL------DDTLVTVTVEQLQNSAN 344

  Rat   338 NDD-CAICWDSM-------------QAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSL------ 382
            :|: |.||.|.:             :..::|||||:.|.|||::|:|:..:||.||:.:
Yeast   345 DDNICIICMDELIHSPNQQTWKNKNKKPKRLPCGHILHLSCLKNWMERSQTCPICRLPVFDEKGN 409

  Rat   383 ----------------NIADGSRAREDHQGENLDENLVP 405
                            .:.|.:....|.||...:.:|:|
Yeast   410 VVQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLP 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	81/378 (21%)
		RING-H2_AMFR	339..382	CDD:319369	20/56 (36%)
		CUE_AMFR	458..498	CDD:270604
		G2BR	575..600	CDD:375868
HRD1	NP_014630.1	HRD1	5..551	CDD:227568	88/429 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910