Protein Alignment Amfr and sip3

DIOPT Version :9

• Sequence 1: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Sequence 2: NP_001263152.1
• Gene: sip3 / 43747
• FlyBaseID: FBgn0039875
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 665
• Identity: 147/665 - (22%)
• Similarity: 259/665 - (38%)
• Gaps: 189/665 - (28%)

  Rat    76 YLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFW--------NFIFY---- 128
            |:...:..:.|:......::.:..||:..|..|.||.:|.:||.::||        .|..:
  Fly    33 YITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETCLAFTVFRDDF 97

  Rat   129 --KFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLI 191
              :|:.:|.|                  |:||.....|.::|.:::..||......|.||.|||.
  Fly    98 NPRFVALFTV------------------LLFLKSFHWLAEERVDFMERSPVLGWLFHIRVGSLLT 144

  Rat   192 AMLLSCCGLAVVCCVTGYTHGM-----HTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWE 251
            .:.:    |..|..:..|...:     ..|.|....::|:|| .|...::||:|..::..:..||
  Fly   145 VLGI----LDYVLLIHAYNSTLVRGPTVQLVFGFEYAILLTV-IASTAIKYVLHAAEMRTDTPWE 204

  Rat   252 GKGTYVYYTDFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYL 316
            .|..::.||:.|:.|:.:.|       .:||..|...:.:|.:|: .|.:|..: |..|:..|.:
  Fly   205 NKAVFLLYTELVIGLIKVVL-------YILFVVIMAKIYALPMFV-FRPMFFTI-RNFRKALNDV 260

  Rat   317 ----RVVGNMEARFAVATAEELAVNNDDCAICWDSM-QAARKLPCGHLFHNSCLRSWLEQDTSCP 376
                |.:.||...:..||.|||..:::.|.||.:.| ..::||||||:||.:|||||.::..:||
  Fly   261 IMSRRAIRNMNTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCP 325

  Rat   377 TCRMSL---------------------------------------------NIADGSRAREDHQG 396
            |||:::                                             .:.||::||.|
  Fly   326 TCRLNILRTPTVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARAD--- 387

  Rat   397 ENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIASWLPSFS--------VEVMHTTNIL------ 447
                   |.||..:..|. |..:.|  .|.|.:.:.||:.:        |..|.:..::
  Fly   388 -------VNVAGGQALPP-NFADLF--GDASGLPNGLPNLAGLQIPPPPVMPMISPFMIPPHFGY 442

  Rat   448 -----------GITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNI-------- 493
                       .:|..::.:|.||....::       |:| |.|::.:::.:..|:.
  Fly   443 LTPLPPPPIPQDLTNFTDEELRAMEGLQRD-------HIV-QRLKLLQNINLMLDSAGIMMSQYQ 499

  Rat   494 -LEGRIQVPFPVQRSDSLRP--ALNSPVERPGTDLEEGEASVQTERVPLDLSPRLEETLDFSEVE 555
             |..|:|:       .::.|  |:|...:....|:....|:...:.....::|....:.....:.
  Fly   500 SLSARLQL-------TAVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMP 557

  Rat   556 LEPVEVEDFEARGSRFSKSADERQRMLVQRKDDLLQQARKRFLNKSSEDDGASERLLPSEGTSSD 620
            .|.|.:||..|       .|||         ||:...|.:.....:|:.|        .|..||:
  Fly   558 AEKVTIEDLGA-------DADE---------DDIPSTATEAVSIPNSDAD--------FEENSSE 598

  Rat   621 PVTLRRRMLAAAAER 635
            ...||:|.|....||
  Fly   599 LGELRKRRLKFLEER 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	89/319 (28%)
		RING-H2_AMFR	339..382	CDD:319369	22/43 (51%)
		CUE_AMFR	458..498	CDD:270604	8/48 (17%)
		G2BR	575..600	CDD:375868	6/24 (25%)
sip3	NP_001263152.1	HRD1	20..>365	CDD:227568	90/363 (25%)
		zf-RING_2	287..328	CDD:290367	20/40 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D271732at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920