Protein Alignment Amfr and AMFR

DIOPT Version :9

• Sequence 1: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Sequence 2: NP_001310441.1
• Gene: AMFR / 267
• HGNCID: 463
• Length: 675
• Species: Homo sapiens
• Alignment Length: 675
• Identity: 603/675 - (89%)
• Similarity: 617/675 - (91%)
• Gaps: 32/675 - (4%)

  Rat     1 MPLLFLERFPWPSLRTYTGLSGLALLGTIVSAYRALSQPEDGSGEPEPLTAPLQPEALAPARLTP 65
            |||||||||||||||||||||||||||||:||||||||||.|.|||:.|||.||||..||||.:.
Human     1 MPLLFLERFPWPSLRTYTGLSGLALLGTIISAYRALSQPEAGPGEPDQLTASLQPEPPAPARPSA 65

  Rat    66 GGPRVRDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKF 130
            ||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human    66 GGPRARDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKF 130

  Rat   131 IFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLIAMLL 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
Human   131 IFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLL 195

  Rat   196 SCCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYT 260
            ||||||.||.:||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   196 SCCGLAAVCSITGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYT 260

  Rat   261 DFVMELMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEAR 325
            ||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   261 DFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEAR 325

  Rat   326 FAVATAEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADGSRA 390
            |||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||.:|.
Human   326 FAVATPEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADNNRV 390

  Rat   391 REDHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDG----------------------------- 426
            ||:|||||||||||||||||||||||||||||||||
Human   391 REEHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDGDDSSMRVTAPEDVPVGQEVEVVDSDTDAP 455

  Rat   427 ---SRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEI 488
               |||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||
Human   456 DLWSRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEI 520

  Rat   489 TTDNILEGRIQVPFPVQRSDSLRPALNSPVERPGTDLEEGEASVQTERVPLDLSPRLEETLDFSE 553
            |||||||||||||||.|||||:|||||||||||.:|.||||.|.|||||||||||||||||||.|
Human   521 TTDNILEGRIQVPFPTQRSDSIRPALNSPVERPSSDQEEGETSAQTERVPLDLSPRLEETLDFGE 585

  Rat   554 VELEPVEVEDFEARGSRFSKSADERQRMLVQRKDDLLQQARKRFLNKSSEDDGASERLLPSEGTS 618
            ||:||.||||||||||||||||||||||||||||:|||||||||||||||||.|||..|||||.|
Human   586 VEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNKSSEDDAASESFLPSEGAS 650

  Rat   619 SDPVTLRRRMLAAAAERRLQRQQTT 643
            ||||||||||||||||||||:|||:
Human   651 SDPVTLRRRMLAAAAERRLQKQQTS 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	289/295 (98%)
		RING-H2_AMFR	339..382	CDD:319369	42/42 (100%)
		CUE_AMFR	458..498	CDD:270604	38/39 (97%)
		G2BR	575..600	CDD:375868	23/24 (96%)
AMFR	NP_001310441.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83696252
Domainoid	1	1.000	606	1.000	Domainoid score	I4753
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H888
Inparanoid	1	1.050	1176	1.000	Inparanoid score	I4231
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG55068
OrthoDB	1	1.010	-	-		D105040at32523
OrthoFinder	1	1.000	-	-		FOG0006872
OrthoInspector	1	1.000	-	-		oto136614
orthoMCL	1	0.900	-	-		OOG6_105132
Panther	1	1.100	-	-	LDO	PTHR15067
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.410