Protein Alignment Amfr and hrd1

DIOPT Version :9

• Sequence 1: XP_038954087.1
• Gene: Amfr / 361367
• RGDID: 1311551
• Length: 643
• Species: Rattus norvegicus
• Sequence 2: NP_596376.1
• Gene: hrd1 / 2539900
• PomBaseID: SPBC17D11.02c
• Length: 677
• Species: Schizosaccharomyces pombe
• Alignment Length: 684
• Identity: 138/684 - (20%)
• Similarity: 244/684 - (35%)
• Gaps: 189/684 - (27%)

  Rat    74 AQYLLSDS-LFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVL 137
            |..::|.| :.:.:.:|...|:...:|..::.::||.|:..|.:.|.::||       |.:..::
pombe    31 ATVMISQSPVHITIGLNVCLCLFFAIANALKTLLFGSLQTFELELLYEQFW-------ITLTEIM 88

  Rat   138 NVQTV--EEV-VMWCLWFAGLVFLHLMVQLCKDRFEYLSFSPT-------TPMSSHGRVLSLLIA 192
            ...||  |.: :.:.:..:.|:|..:...:|..|.|.|....|       :.::....|||:|.|
pombe    89 LAITVFREAISISFFMLLSTLMFARVFHSICSFRTERLQIQLTDQRFHIFSRLTCAYFVLSILDA 153

  Rat   193 MLLSCCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNH-EGTWEGKGTY 256
            .|:      .:|..:.:.....|......|..::.:.......:..|:|::..| :..|:.|.||
pombe   154 SLI------YLCFTSEHLGDKSTRMLFVCEFSVLLLNLTIEASKLCIYLYEARHLDQVWDEKSTY 212

  Rat   257 VYYTDFVME-LMLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVG 320
            ::..:...: |.||:..|   :.|..|..:.:.:.|:   .|:...|:.:.||||.|..:.:...
pombe   213 LFRLEVCRDGLRLLAYSL---LFMYQFPYVSVPIYSI---RQMYTCFYSLFRRIREHARFRQATR 271

  Rat   321 NMEARFAVATAEELAVNNDDCAICWDSM---------------------QAARKLPCGHLFHNSC 364
            :|.|.:..||.|:|..::..|.||.:.|                     ...::|||||:.|..|
pombe   272 DMNAMYPTATEEQLTNSDRTCTICREEMFHPDHPPENTDEMEPLPRGLDMTPKRLPCGHILHFHC 336

  Rat   365 LRSWLEQDTSCPTCRMSLNIADGSRAREDHQGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRI 429
            ||:|||:..:||.||.|:            .|.......:|.:     |.:.         .::|
pombe   337 LRNWLERQQTCPICRRSV------------IGNQSSPTGIPAS-----PNVR---------ATQI 375

  Rat   430 ASWLPSFSVEVMHTTNILGITQASN------SQLNAM--------AHQIQEMFPQVPYHLVLQDL 480
            |:.:|: ......||.:.|||.:||      |..|.:        |...|::...:|..:.|:|
pombe   376 ATQVPN-PQNTPTTTAVPGITNSSNQGDPQASTFNGVPNANSSGFAAHTQDLSSVIPRRIALRD- 438

  Rat   481 QMTRSVEITTDNILEGRIQVPFPVQR------------SDSLRPALNSP---------------- 517
                           |...:|.|..|            :.|..|....|
pombe   439 ---------------GWTMLPIPGTRRIPTYSQSTSTTNPSATPTTGDPSNSTYGGPQTFPNSGN 488

  Rat   518 ----------VERPG-----------------TDLEEGEASVQTERVPLDLSPRLEETLDFSEVE 555
                      :..||                 |.|.:..:|...     :|...|...:..|...
pombe   489 NPNFNRGIAGIVPPGWRLVSSNTQSLSTNSAMTSLYQNASSADN-----NLGSSLPNVVPLSRGL 548

  Rat   556 LEPVEVED-FEARGSRFSKSADERQRMLVQRKDDLLQQARKRF----------LNKSSEDDGASE 609
            .:..|..: |.|..|..|....|     :..|.|.|::....|          ||:.....|.:|
pombe   549 TQSNETSNTFPAASSNISSQLRE-----LHTKIDELRETVSNFRADYNSIRTSLNQLEAASGINE 608

  Rat   610 RLLPSEGTSSDPVTLRRRMLAAAAERRLQRQQTT 643
            |:   :.||:|.:.....|.........|...||
pombe   609 RI---QTTSADSLLNSNGMSGTEGFENTQTSITT 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Amfr	XP_038954087.1	HRD1	86..>382	CDD:227568	77/328 (23%)
		RING-H2_AMFR	339..382	CDD:319369	20/63 (32%)
		CUE_AMFR	458..498	CDD:270604	7/47 (15%)
		G2BR	575..600	CDD:375868	6/34 (18%)
hrd1	NP_596376.1	HRD1	1..514	CDD:227568	110/544 (20%)
		zf-RING_2	291..351	CDD:290367	18/59 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910