Protein Alignment mms4 and Eme1

DIOPT Version :10

• Sequence 1: NP_610611.1
• Gene: mms4 / 36136
• FlyBaseID: FBgn0033549
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_001366617.1
• Gene: Eme1 / 268465
• MGIID: 3576783
• Length: 589
• Species: Mus musculus
• Alignment Length: 368
• Identity: 93/368 - (25%)
• Similarity: 155/368 - (42%)
• Gaps: 89/368 - (24%)

  Fly    15 EQQKRIK---PGECMKYVRMVIDAGFLGIPVGQEALQQLNA--TGLKYEIRSLPVSHCILWERN- 73
            |..||:|   |.||:|::.:|:|...|.:..|.:.|..|.|  .....|::::|.|  |.|.|.
Mouse   234 EMIKRLKAQRPEECLKHIVVVLDPVLLQMEGGGQLLGALQAMECSCVIEVQAIPRS--ITWRRRR 296

  Fly    74 -------VGQQTIALGSSP------TGLDEAWKSENQV---------------VQWLSESSFQRA 110
                   |.::. |.||.|      .|.|  |..|..:               ::..|.||.::.
Mouse   297 TELVELPVAERG-ATGSIPFPCLNEDGDD--WMEEPTILVLVLAEVFMSMAYNLKQASPSSTEKG 358

  Fly   111 V---------------KDQSLV------CLGP-----RLQDSFPDCQYTIALPTLRHSKHGSSSS 149
            .               |..|||      |..|     |.:....:.|     ...:|.:...||:
Mouse   359 KETLRSFVTDVTAKTGKALSLVIVDQEKCFRPQNPPRRRKSGMANKQ-----AKAKHQQRQESST 418

  Fly   150 ---------QDALIEMQLLQELHVEQLDQPESQDLVALLQRYTKAIAEAPYKKQRNETLGGFKKY 205
                     :.||:::||..|.....:.  ..::|......:|||:||||:||.|::..  |..:
Mouse   419 GLMVSRADMEKALVDLQLYTEAQAWMVQ--SWKELADFTCAFTKAVAEAPFKKLRDQVT--FSFF 479

  Fly   206 LANDKKQCVRVDQ-GNGYGRLWQQHLNRLPMVTLEVAESIIAQYPCPKKLIDHFS---SDPLAVQ 266
            |..|....::||| |.|...:|::.:.:|..|:.|:|.:|:..||.|:.|:..:.   |:.....
Mouse   480 LEKDWAGGMKVDQSGRGLALIWRRQIQQLNRVSSEMASAIVDAYPSPQLLVQAYQRCFSEQERQN 544

  Fly   267 SLADLKIKRCNGPQPLHTERRIGNVLSNKLYTLYTAKDPNTLI 309
            .|||::::|..|...  |.||:|..||.::|...|...|:.::
Mouse   545 LLADIQVRRGEGVTA--TSRRVGPELSRRIYLQMTTAQPDLIL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mms4	NP_610611.1	XPF_nuclease_EME	28..192	CDD:410859	49/229 (21%)
Eme1	NP_001366617.1	XPF_nuclease_EME1	243..471	CDD:410857	55/239 (23%)