Protein Alignment wde and atf7ip

DIOPT Version :9

• Sequence 1: NP_001286294.1
• Gene: wde / 36133
• FlyBaseID: FBgn0027499
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_005160098.1
• Gene: atf7ip / 558977
• ZFINID: ZDB-GENE-061103-178
• Length: 860
• Species: Danio rerio
• Alignment Length: 1033
• Identity: 243/1033 - (23%)
• Similarity: 377/1033 - (36%)
• Gaps: 281/1033 - (27%)

  Fly   460 TEEPE-NKKEIEDTEELEEPVVIEGEET--EDPQKKV-QKEFDVRTADHEMNYTTIDDKLDEAVK 520
            ||:|: ...:|.:.:....|.:::.|..  |:||||: :....::.:|.:.
Zfish    21 TEDPQATACQIHEQDSSRHPSLVKMEVAVPEEPQKKIFRARKTMKMSDRQQ-------------- 71

  Fly   521 DVVEIEEKKAAEDELGVIPKGDKEPTTNGACEISTDGNLKDLESNESTVVEEETKETESDDEVIF 585
              :|:.....|.....:.....:.|..||. ...|:   |||.:.|..::...|..........|
Zfish    72 --LEVLHNTLATTNSSLSSSPPQTPLMNGT-HTETE---KDLNNKEGDLMAPATDSARCSPSPSF 130

  Fly   586 FEPLDKTENVGTTANPTNENSVKPQAKDDEVVLVSEDEDETPQNGISEKEVQTIQKETALKGLPN 650
                    .|..:.:|.|..:..| |.|.|..||:.:|                :|||:     |
Zfish   131 --------PVSRSPSPPNTQTTSP-AMDLEDPLVATEE----------------KKETS-----N 165

  Fly   651 ESTTESVEAKNLQIDNSDNACDQFEKLKTHDMVKQTTTEDGNSNSSNLLRPAEYAEESVPKRLRL 715
            :|::.|..|....::......:.|..|...|.. |...::.:|:...:...||..::.
Zfish   166 KSSSSSPSASPAGLNCDPEVKEGFLCLSEEDET-QADKDEKDSSEEKMNVDAETEDQK------- 222

  Fly   716 STDEKNEFEAET--NQE---SLPILSRAEGGLKDVTKRSHEHLDSSPQEEIPNKKAKTEDSDSNS 775
              :||:|.:.:|  |.|   |.|:      |||.......:..|...:||...|:|:.|..:..:
Zfish   223 --EEKDEKDTDTPENAEADNSAPV------GLKRTLSEEKDEDDKEIEEERDGKRARLEGEELEA 279

  Fly   776 SHEGTLQIDMGGQEDKEESPKKDTQKKLDFDLNPVPEIKQNVKPLRLEFFKTFRRSFDTMTRDDL 840
            ..|  |:|...|.                                               .||.:
Zfish   280 QLE--LKITANGG-----------------------------------------------NRDKI 295

  Fly   841 EELVLQKVVEAMMVKSDFAEIRMQL---DKCESTLANYRRKIAEVSKQFLDLETVHKRVLKDLEA 902
            |::|.|.|.|.:.|        :||   |:....|.:...||..|:||...|:.::     .|:|
Zfish   296 EKMVQQLVEERLRV--------LQLTVFDRSLKELKDRVEKIDNVTKQQNALQHIN-----TLQA 347

  Fly   903 KNSHFTAPVRITRAVGLQVGIPFKAIKPTVAAPESTHAAGSVLAPPSGTP---------PKASTS 958
            |.|      |:.:..|........| |.|..|..:..||.:..|..:.||         .|.|:|
Zfish   348 KIS------RLAKKFGAANQASENA-KRTQDAQAAAAAAQANNATNATTPQRTVKTTVDSKLSSS 405

  Fly   959 PT--RATVRPRPPPPTFGPSTSSSETGAG-------VSVTPNSNHQQQQPAARSSQSLTTASVTP 1014
            ||  .:|..|..|.|...|:|.:|...|.       :|.|.:|        ..||.||...|.|.
Zfish   406 PTVSNSTAVPAQPKPLSTPATPTSSALATTAPILQIISTTTSS--------TPSSTSLPGQSQTG 462

  Fly  1015 PVRRGCLQKVTPHRPVPTNLQPA-----PMLMNQSSVQRLQSSPPIAQRT------MHASKHTG- 1067
            .:    |.|..|:..|.|| .||     |:.|.|..:|.     |:|...      ::|:...|
Zfish   463 TL----LLKTGPNPTVMTN-APATSGGQPVAMQQLLIQL-----PLAMANGQSGALVNAAGGVGL 517

  Fly  1068 TPGSTPSSVANAINKTVMRARNSEAAFLAQKQQQKQHQQQQQQQQQHLQQQQKQQQAQQQFLLPR 1132
            .|.|:.|:|:| |||.  :.......|:.||...              ........|....|...
Zfish   518 IPVSSLSTVSN-INKA--KTTTPATTFMLQKTAG--------------NVSSATSSAPAVSLARA 565

  Fly  1133 PSPGPT-PGSSPAKQVPKCTTKVRAKQPPLSGATVSVPISSSS--------SGSELGSYGQQQES 1188
            ..||.| ..|||...:...|    |:.|....|.|.|..:::|        :||...:.|....|
Zfish   566 VYPGGTGTVSSPNTGISVTT----ARTPTQCAAVVGVSTAAASPGTTGPAATGSAAAAAGSPSAS 626

  Fly  1189 SLA---------------PAKPKEKAVIDLTDEDDAAAAAAARAAQAQNARLRMEMLKRNAQTAA 1238
            :||               |.:|| .:|||||::||.......:.|..               :..
Zfish   627 ALASKTDNQASTPKTASQPGRPK-GSVIDLTEDDDDVQVTGVQKATV---------------SPV 675

  Fly  1239 ATRGGRGGGNVVRASPMQLPRVNARQIVHNNGGGQQSPLGSNVTMQIRSENTPPPASRLRYSHPA 1303
            .|:...|...:|.::|             |.|.|.:|...|.|....:|.   |.:|......|.
Zfish   676 TTQRSSGPPPLVSSTP-------------NTGTGVRSAQRSTVDSPSQSR---PSSSSSTSLPPL 724

  Fly  1304 PLPTSPPQPFNP--SWKVPPSRPVIRISLLDT--GIVISWTLEDSSPRFAECVMYQIYAY----Q 1360
            ||..|||....|  :...||.:|.::::.:.:  |||:||.:.::....|....|.:|||    |
Zfish   725 PLAPSPPARLPPEANHTSPPQQPQLKLARVQSQNGIVLSWCVAETDRNCAAVDTYHLYAYHQDHQ 789

  Fly  1361 ETINEPSTDS-WRHVGDVSAMLLPMAVTLNQFQENQRYYFAVRGVDSHERFGPFSVPK 1417
            .:::..|... |:.:|:|.|:.||||.||.||.....||||||..|.:.|||||..|:
Zfish   790 SSVSGASAQMLWKKIGEVKALPLPMACTLTQFVSGSTYYFAVRAKDVYGRFGPFCEPQ 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wde	NP_001286294.1	fn3_4	1320..1418	CDD:293399	40/105 (38%)
atf7ip	XP_005160098.1	PPP4R2	<84..229	CDD:286293	37/188 (20%)
		ATF7IP_BD	267..>433	CDD:293393	52/234 (22%)
		fn3_4	743..848	CDD:293399	40/105 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582053
Domainoid	1	1.000	77	1.000	Domainoid score	I8854
eggNOG	1	0.900	-	-		E1_28K6G
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007416
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23210
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.890