Protein Alignment wde and Atf7ip

DIOPT Version :10

• Sequence 1: NP_610608.1
• Gene: wde / 36133
• FlyBaseID: FBgn0027499
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_063142223.1
• Gene: Atf7ip / 312800
• RGDID: 1306030
• Length: 1317
• Species: Rattus norvegicus
• Alignment Length: 1582
• Identity: 331/1582 - (20%)
• Similarity: 517/1582 - (32%)
• Gaps: 544/1582 - (34%)

  Fly     2 MGVNQTMELKELSTEEALMRTLSTELGNEV--EPLS-TPAILNESSQTSVDEVDLCELTNGVDSS 63
            :||....|  :|:: |||..:::::|.::|  ||.| |||..|....|...:...|:..    :|
  Rat   105 VGVKNKQE--DLNS-EALSPSITSDLASKVTTEPASGTPASDNPGCDTLASDNPGCDTL----AS 162

  Fly    64 DNVKVIDKPKKISDRERNPGS-DLDA--LLDKISSI-------VDCSPRNSDDIDSLDR--DEEC 116
            || ...|.|...:....|||| ||.|  |..::.:.       :..|..:|.|..|.|.  .:.|
  Rat   163 DN-PASDNPASDNPASDNPGSGDLAAGELTTRVPTAGESACEELPSSHPSSSDPSSSDPTFSDPC 226

  Fly   117 DSASAKKRTAAD--TDENLKEQREKPEEEEEGEEVLSSLEGEECIDP-DSELKTEEKLDETEEHA 178
            .|......||::  |.:.|........:...||.|..        :| .||..:||::  |...|
  Rat   227 CSDPVSGDTASEEPTSDALASGDSASGDSASGEPVSH--------EPASSEPASEERV--TGAVA 281

  Fly   179 SAKESTQKTEDLADSDEILKSKEEDEVPANTADNIEKDRKNTSTDDVFMYALDCISSADEFDAFA 243
            |.        |||..:..|.                                ||::|.|
  Rat   282 SC--------DLASGESALD--------------------------------DCVTSGD------ 300

  Fly   244 SQDSKKAKPSKKLNTENNSSVNDLEDISSDDDDIIKETEKPNTEVIDLDSSSECVP--------- 299
                                        |..||:....|...|.|....:|.|.:|
  Rat   301 ----------------------------SPSDDLPSSEESLRTSVCSRLASGELIPGELTVESAT 337

  Fly   300 ----------CEAESEVEETEANT----------EDTEVLTHGKVSTKKSLN----LQNNISEKS 340
                      ||...:.::||.|:          :|.|.|  .::.:|.:.:    :.:|::||.
  Rat   338 DSFKPSSVPVCEPGPDTDKTEQNSKNNDDCPDRNDDDEDL--AQIQSKDAFDEGNKVNSNVAEKE 400

  Fly   341 ASAAEYESVKADQHLTEGKEPMLVGDEVTEKSKESIPIQSEESIQVDEPEESKESEELEEHKEKE 405
            .:...:.::....||.......:..|.|.|.:.|...|.|  |::||:.|:
  Rat   401 GTLETHSAIIHSDHLPPENTKKVEEDAVAEPALEEEAISS--SMEVDQSEK-------------- 449

  Fly   406 EPDYCKETKDSEEATEKEKSEIKIIKASKVAQILGDTKEEEDPSPTQEVEDVKETEEPENKKEIE 470
                           ::.||.::::.|:           .|||           |||.:.....:
  Rat   450 ---------------DRHKSPVELVDAA-----------SEDP-----------TEEGKKNTVSD 477

  Fly   471 DTEELEEPVVIEGEETEDPQKKVQKEFDVRTADHEMNYTTIDDKLDEAVKDVVEIEEKKA-AEDE 534
            :|:.:|                                          ..:::.|.||.| .|||
  Rat   478 NTDSME------------------------------------------TDEIIPILEKLAPTEDE 500

  Fly   535 LGVIPKGDKEPTTNGACEISTDGNLKDLESNESTVVEEETKETESDDEVIFFEPLDKTENVGTTA 599
            |....|....|.                             ||..|.|       ||.|  |:..
  Rat   501 LSCFSKTSLLPV-----------------------------ETSQDLE-------DKME--GSFG 527

  Fly   600 NPTNENSVKPQAKDDEVVLVSEDEDETPQNGISEKEVQTIQKETALKGLPNESTTESVEAKNLQI 664
            :|:.:.|.:...|  |..||..||::. ..|..|.||....|.::.:|..:|..:::.|.|.:..
  Rat   528 SPSKQESSENLPK--EAFLVLSDEEDI-SCGKDESEVLAQNKTSSPEGERSEKDSKAEEEKRVPD 589

  Fly   665 DNSDNACDQFEKLKTHDMVKQTTTEDGNSNSSNLLRPAEYAEESVPKRLRLSTDEKNEFEAETNQ 729
            :......::|.:.      |::.:||.:|..|...|   |.||              |:|||
  Rat   590 EERPPGRNEFSRR------KRSKSEDMDSVQSKRRR---YMEE--------------EYEAE--- 628

  Fly   730 ESLPILSRAEGGLKDVTKRSHEHLDSSPQEE------------IPNKKAKTEDSDSNSSHEGT-- 780
              ..:...|:|   |:.::..:.:....:|:            :...|.:.|..:.|..|:..
  Rat   629 --FQVKITAKG---DINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIECNKRHKAVLT 688

  Fly   781 -LQIDMGGQEDKEESPKKDTQKKLDFDLNPVPEIKQNVKPLRLEFFKTFRRSFDTMTRDDLEELV 844
             ||..:.....:..:.|.|.:|:.:..  |.|.|... ||..
  Rat   689 ELQAKIARLTKRFGAAKDDLKKRQESP--PNPPISPG-KPAN----------------------- 727

  Fly   845 LQKVVEAMMVKSDFAEIRMQLDKCESTLANYRRKIAEVSKQFLDLETVHKRVLKDLEAKNSHFTA 909
                                 |...:....||.  |...:|.|:    .||.:.  |.....|..
  Rat   728 ---------------------DVNSNNNVTYRN--AGTVRQLLE----SKRNIS--EGPPPSFQT 763

  Fly   910 PVRI---------TRAVGLQVGIPFKAIKPTV-AAP----ESTHAAGSVLAPPSGTP-PKASTSP 959
            ||..         :.||..|..:...|...:: |||    .||....:....|||.| |..|..|
  Rat   764 PVNTVSSASHGPSSAAVSSQPKVQPSATSGSLPAAPLLPVPSTATVVATTQVPSGNPQPTISLQP 828

  Fly   960 TRATVRPRPPPPTFGPSTSSSETGAGVSVTPNSNHQ----QQQPAARSSQSLTTASVT-PPVRRG 1019
            ....:.. |...|..|....|..|..|:..|:.|.:    |.||..   ..||...|: ||:
  Rat   829 LPVILHV-PVAVTSQPQLLQSHPGTLVTNQPSGNVEFISVQSQPTV---SGLTKTPVSLPPL--- 886

  Fly  1020 CLQKVTPHRP-VPTNLQPAPMLMNQSS-----------VQRLQSSPPIAQRTMHASKHTGTPG-- 1070
                ..|.:| :|:  .|:|.:...||           ||.:.::..|.|.|..:....|..|
  Rat   887 ----PNPTKPNIPS--VPSPSIQRNSSATAAPLGTTLAVQAVPTAHSIVQATRTSLPPVGPSGLY 945

  Fly  1071 ------------------STPSS----------VANAINKTVMRARNSEAAFLAQKQQQKQHQQQ 1107
                              ||.||          ..|..||||..|.|.:||....:..:......
  Rat   946 SSSSSRGSIQMKIPIPAFSTSSSAEQSSSATPRAENQTNKTVDSAVNKKAADSTSQSGKASSNDS 1010

  Fly  1108 -------QQQQQQHLQQQQKQ--------------QQAQQQFLLPRP--SPGPTPGSSPAKQ--- 1146
                   ...:.....|..|:              .....|.:||.|  .|...|.|.|::.
  Rat  1011 SGVIDLTMDDEDSGTTQDPKKLNPPSASTVSTSQPMSRPLQPILPAPPLQPSGVPTSGPSQATIH 1075

  Fly  1147 -VPKCTTKVRAKQPPLSGATVSVPISSSSSGSELGSYGQQQESSLAPAKPKEKAVIDLTDEDDAA 1210
             :|...|.|.....|::..|..:|:..:.:       ..|...:..|| |..:|.:..|    ..
  Rat  1076 VLPTAPTTVNVTHRPVTQVTTRLPVPRAPA-------NHQVVYTTLPA-PTTQAPLRGT----VM 1128

  Fly  1211 AAAAARAAQAQNA-RLRMEMLKRNAQTAAATRGGRGGGNVVRASPMQLPRVNARQIVHNNGGGQQ 1274
            .|.|.|....||: .:|:............|.|..|....|...|.|         |||.
  Rat  1129 QAPAVRQVNPQNSVTVRVPQTTTYVVNNGLTLGSAGPQLTVHHRPPQ---------VHNE----- 1179

  Fly  1275 SPLGSNVTMQIRSENTPPPASRLRYSHPAPLPTS------PPQPFNPSWKVPPSRPVIRISLLDT 1333
                             ||    |..||||||.:      ||:..|.|.   |.:|.::::.:.:
  Rat  1180 -----------------PP----RPLHPAPLPEAPQPQRLPPEAANTSL---PQKPHLKLARVQS 1220

  Fly  1334 --GIVISWTLEDSSPRFAECVMYQIYAYQETINEPSTDSWRHVGDVSAMLLPMAVTLNQFQENQR 1396
              |||:||::.:.....|....|.:|||.|..:..:...|:.:|:|.|:.||||.||.||....:
  Rat  1221 QNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATAPSQWKKIGEVKALPLPMACTLTQFVSGSK 1285

  Fly  1397 YYFAVRGVDSHERFGPFSVPKT 1418
            ||||||..|.:.|||||..|::
  Rat  1286 YYFAVRAKDIYGRFGPFCDPQS 1307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wde	NP_610608.1	PTZ00121	<154..818	CDD:173412	125/713 (18%)
		DUF5585	<927..>1074	CDD:465521	45/189 (24%)
		fn3_4	1320..1418	CDD:465273	38/99 (38%)
Atf7ip	XP_063142223.1	None