Protein Alignment wde and atf7ip

DIOPT Version :9

• Sequence 1: NP_001286294.1
• Gene: wde / 36133
• FlyBaseID: FBgn0027499
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_012816910.1
• Gene: atf7ip / 100490711
• XenbaseID: XB-GENE-6460810
• Length: 1269
• Species: Xenopus tropicalis
• Alignment Length: 1403
• Identity: 324/1403 - (23%)
• Similarity: 527/1403 - (37%)
• Gaps: 341/1403 - (24%)

  Fly   208 NTAD----NIEKDRKNTSTDDVFMYALDCISSADEFDAFASQDSKKAKPSKKLNTENNSSVNDLE 268
            :||:    .:.|.||.....|  ...||.:..|.|         :..||::......|....|::
 Frog     7 DTAEEPQKKVFKARKTMKASD--RQQLDAVHKAKE---------ELIKPTEVKLLNGNHENGDMD 60

  Fly   269 DISSDDDDIIKETEKPNTEVIDLDSSSECVPCEAESEVEETEANTEDTEVLTHGKVSTKKSLNLQ 333
            .|:  ::|.:.|.::.| .:|:::|....||....|:::|...|.|.|:.|       |..|.||
 Frog    61 IIA--ENDFVTERKELN-GMIEVNSEPHEVPIVKLSDIKEGLINLEQTKDL-------KLKLELQ 115

  Fly   334 NNIS------EKSASAAEYESVKADQHLTEGKEPMLVGDEVTEKSKESIPIQSEESIQVDEPEES 392
            :..|      |.|||..|                            :::|:.|      |..||.
 Frog   116 HTESPVCQDNETSASVCE----------------------------DAVPVSS------DNKEEQ 146

  Fly   393 KESEELEEHKEKEE--PDYCKETKDSEEATEKEKSEIKIIKASKVAQILGDTKEEEDPSPTQEVE 455
            .|....:..:|:..  ..:.|:|.|:|  ..:|:||:......:...:|....|.||..|.   |
 Frog   147 HEVTNTDAAQEEAASLQSFDKKTTDTE--LSEEQSEVNNSGEEESHIVLDGIHELEDDIPE---E 206

  Fly   456 DVKETEEPENKKEIEDTEELEEPVVIEGEETEDPQKKVQKEFDVRTADHEMNYTTIDDKLDEAVK 520
            ||.|....|   |..|.|..|:..:::||:                .::::..:|.:..:...|.
 Frog   207 DVNERAFAE---ENMDVEHKEQEKIVQGED----------------ENNDLKDSTDEQGVQSDVA 252

  Fly   521 DVVEIEEKKAAEDELGV-IPKGDKEP---TTNGACEISTDGNLKDLESNESTVVEEETKETESDD 581
            :..|:..||..:.|... :.|.:.||   |.|.|.......::.|.:..|....:.:.::.|...
 Frog   253 EGTELSRKKEEQQETTENVSKQETEPEGKTENAASTPEITNDIADGQQEEEAPQDMDMEQEEGCS 317

  Fly   582 EVIFFEPLDKTENVGTTAN---------PTNENSVKPQAKDDEVVLVSEDEDETPQNGISEKEVQ 637
            |       :|:|||.|||.         ..||.::....:.|:.:.|.|.:....|....||.|.
 Frog   318 E-------EKSENVETTAENIETPADELQPNEEAISSSMETDQSIKVEEQKCSGVQEATLEKSVS 375

  Fly   638 TIQKETALKGLPNESTTESVEAKNLQIDNSDNACDQFEK--LKTHDMVKQTTTEDGNSNSSNLLR 700
            .||..:.|:......|.|.:..........|...| |||  |.:..:......:.||
 Frog   376 EIQTASGLESPDTMETDEIIPILEKLAPVEDEPLD-FEKNHLNSESIADSEEQKAGN-------- 431

  Fly   701 PAEYAEESVPKRLRLSTDEKNEFEAETNQESLPILSRAEGGLKDVTKRSHEHLDSSPQEEIPNK- 764
                 ||:.|.:             :.|:|:||  |.|...|.|..:.|.|.  |||.||....
 Frog   432 -----EETSPSK-------------QDNRETLP--SEAFLVLSDEEEPSDER--SSPVEEKTTSA 474

  Fly   765 ----KAKTEDSDSNSSHEGTLQIDMGGQEDKEES---PKKDTQKKL--DFDLNPVPEIKQNVKPL 820
                .|.||.:..:...||         |.||||   |:.:|.:..  :..|..|...|:: |..
 Frog   475 PQAIDADTETAKKSGEKEG---------EQKEESVKEPQAETSEVSPDEVSLGEVSRRKRS-KSE 529

  Fly   821 RLEFFKTFRRSFD----------TMTRDDLE---ELVLQKVVE-------AMMVKSDFAEIRMQL 865
            ..|...:.||.::          .:|.|||.   :.|:||::|       .::.....|:::.::
 Frog   530 DFESESSKRRRYEGEEYEAELQVKITADDLNKKLQNVIQKMLEERLSTLQCVVFDKTLADLKTRV 594

  Fly   866 DK--C---ESTLANYRRKIAEVSKQF----LDLE------------TVHKRVLKDLEAKNS---H 906
            :|  |   |:.|...:.|||.::|:|    .||:            :..|.|.:...|.||   .
 Frog   595 EKIECKKHENILYAIQAKIARLTKRFGAAKEDLKKRPEQSTAVNPASPGKTVNEASTANNSMNYR 659

  Fly   907 FTAPVRITRAVGLQVGIPFKAIKPTVAAPESTHAAGSV--LAPPSGTPPKASTSPTRATVRPRPP 969
            ..:.||........||.....::|:..|..||....|:  ..|.:.|....|.|....:::.|.|
 Frog   660 SASTVRQMLESKRNVGETVTILQPSTTAQPSTPTTSSLPHRTPNTTTQVSVSQSTANTSLQGRAP 724

  Fly   970 P--PTFGPSTSSSETGAGVSVTP-NSNHQQQQP-----AARSSQSLTTASVTPPVRRGCLQKVTP 1026
            |  .......::|..|     || ||.:.|.:|     :|....|:..|:.|..|........:.
 Frog   725 PDWKLIQQRINASSIG-----TPQNSLNNQNKPLPPVTSAPVMTSVIPATTTATVVGNSQVSGSS 784

  Fly  1027 HRPVPTNLQPAPMLMN-----QSSVQRLQSSPPIAQRTMHASKHTGT----PGSTPSSVAN---- 1078
            .:|:..:||..|::::     ||..|.:|.:    ..|:..::.:|.    |...|||::|
 Frog   785 SQPMSVSLQSLPVILHVPVAMQSQSQLMQGT----TGTLVTNQQSGNVEFIPVQNPSSISNLTKA 845

  Fly  1079 -AINKTVMRARNSEAAFLAQKQQQKQHQQQQQQQQQHLQQQQKQQQAQQQFLLPRPSPGPTPGSS 1142
             .::.|..:..||.:  :.....|:............:|.........|.   .|||...|..|.
 Frog   846 SPVSLTPNKPVNSPS--MPSPSIQRNSPGNSVSSTLTVQSIPTTHSVAQS---SRPSLPSTASSG 905

  Fly  1143 PAKQVPKCTTKVRAKQPPLSGATVSVPISSSSSGSELGSYGQQQESSLAPAKPKEK--------- 1198
            ...|....||.  ..:.||||........::||..||    |...:|.:.:.|.::
 Frog   906 IYNQANNRTTS--QLKSPLSGFNSPSSAEATSSSREL----QTNRTSTSESVPSKRVVENSTAGG 964

  Fly  1199 ---AVIDLT-DEDD---AAAAAAARAAQAQNARLRMEMLKR-------NAQTAAATRGG------ 1243
               .||||| ||:|   .:..:...:....:..::.:|:.|       ||..:.:|...
 Frog   965 KPGGVIDLTLDEEDIEITSQDSRRTSTSGLSGNIQPQMISRPPQLPQPNALQSPSTSANIPSQAT 1029

  Fly  1244 ---------------RGGGNVVRASPMQLPRVNARQIVHNNGGGQQSPLGS---NVTMQIRSENT 1290
                           |.|..:.|.|..:.|  |.:|:|:.......:|:.:   |..||...:.|
 Frog  1030 IHVLPTAQTTVNITQRPGTQMTRTSAPRTP--NNQQMVYTTSSLPTAPIQTPVRNTVMQNLRQIT 1092

  Fly  1291 P-----------------------------------PPASRLRYSHPAPLPTSP-PQ--PFNPSW 1317
            |                                   ||....|..||||||.:| ||  |...:.
 Frog  1093 PQTGGVPVRMQQTAAYVVNNGMTMGSSGPQLTVHHRPPQETARPIHPAPLPEAPQPQRLPQEAAG 1157

  Fly  1318 KVPPSRPVIRISLLDT--GIVISWTLEDSSPRFAECVMYQIYAYQETINEPSTDSWRHVGDVSAM 1380
            ..||.:|.::::.:.:  |||:||::.:.....|....|.:|||.|..|..|...|:.:|:|.|:
 Frog  1158 TSPPQKPHLKLARVQSQNGIVLSWSVLEVDRTCAIVDSYHLYAYHEDPNATSPSQWKKIGEVKAL 1222

  Fly  1381 LLPMAVTLNQFQENQRYYFAVRGVDSHERFGPFSVPKT 1418
            .||||.||.||....:||||||..|...|||.|..|::
 Frog  1223 PLPMACTLTQFVSGSKYYFAVRAKDIFGRFGQFCDPQS 1260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wde	NP_001286294.1	fn3_4	1320..1418	CDD:293399	40/99 (40%)
atf7ip	XP_012816910.1	MDN1	<94..464	CDD:227596	103/472 (22%)
		ATF7IP_BD	533..788	CDD:374802	56/259 (22%)
		Atrophin-1	619..>1149	CDD:367360	114/551 (21%)
		fn3_4	1160..1260	CDD:374807	40/99 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8396
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4058
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007416
OrthoInspector	1	1.000	-	-		otm47882
Panther	1	1.100	-	-	LDO	PTHR23210
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.150