Protein Alignment wde and atf7ip2

DIOPT Version :10

• Sequence 1: NP_610608.1
• Gene: wde / 36133
• FlyBaseID: FBgn0027499
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_012826363.1
• Gene: atf7ip2 / 100489429
• XenbaseID: XB-GENE-6045764
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 976
• Identity: 180/976 - (18%)
• Similarity: 316/976 - (32%)
• Gaps: 318/976 - (32%)

  Fly   491 KKVQKEFDVRTADHEMNYTTIDDKLDEAVKDVVEIEEKKAAEDELGVIPKGDKEPTTNGACEIST 555
            ||:.:.....||........: :||....|:.:.:|...:.....||   ...|.::...|...|
 Frog    34 KKIFRAKKTMTASCRQQIAIL-NKLKSCTKEGIAVEGLTSLLPTDGV---QQSERSSKANCPEQT 94

  Fly   556 DGNL-KDLESNESTVVEEETKETESDDEVIFFEPLDKTENVG---------TTANPTNENSVKPQ 610
            :..| |.|||....:...|.|        :....::...|.|         ::|:..:.......
 Frog    95 NSKLSKSLESLNQNIFSNELK--------VSVAQINSRSNTGYSYKEAFGISSASEKSHGHFSTS 151

  Fly   611 AKDDEVVLVSEDEDETPQNGISEKEVQ-------TIQKETALKGLP-----NESTTESVEAKNLQ 663
                   :|:.|......:|.::::..       .:|.....|||.     :|...|:..:||.|
 Frog   152 -------MVTADVSHNANSGFTKQKADYSSPKKPPLQSSPVSKGLQHLKSFSEKIKENSNSKNDQ 209

  Fly   664 IDNSDNA--C---DQFEKLKTHDMVKQTTTEDGNSNSSNLLRPAEYAEESVPKRLRLSTDEKNEF 723
            ..|||.|  |   |..|.:|.......:|....||.||..
 Frog   210 NPNSDLALPCHIKDNTENIKGQSKKTFSTVHVQNSTSSIF------------------------- 249

  Fly   724 EAETNQESLPILSRAEGGLKDVTKRSHEHLDSSPQEEI---PNKKAKTEDSDSNSSHEGTLQIDM 785
                             ||.::::.:.:.|.::....|   ..|:..:|.:|.:........:::
 Frog   250 -----------------GLNNLSESTTQDLSNNCDTSIGANQRKRVHSESNDVSCCKRNNASLNV 297

  Fly   786 GGQEDKEESPKKDTQKKLDFDLNPVPEIKQNVKPLRLEFFKTFRRSFDTMTRDDLEELVLQKVVE 850
            ..:.:|               :|.:.|..|.:...|::.|  |:.|.| ...:||..
 Frog   298 CSEPEK---------------INVILEKIQCLIENRIQSF--FKESLD-QRMEDLSR-------- 336

  Fly   851 AMMVKSDFAEIRMQLDKC----ESTLANYRRKIAEVSKQFLDLETVHKRVLKDLEAKNSHFTAPV 911
                       |:.|.||    .:.:|.||||..::.::...:.:|.|...|  :..|.|
 Frog   337 -----------RVSLIKCMGNHGNDIARYRRKARKLERRIKSVLSVQKEAEK--QRNNLH----- 383

  Fly   912 RITRAVGLQVGIPFKAIKPTVAAPESTHAAGSVLAPPSGTPPKASTSPTRATVRPRPPPPTFGPS 976
            .|.|                    |........||.......|.|.|.:..||          .:
 Frog   384 NIKR--------------------EKVATVNDKLASDQKLLSKESLSSSPKTV----------IT 418

  Fly   977 TSSSETGAGVSVTPN---SNHQQQQPAARSSQSLTTASVTPPVRRGCLQKVTPHRPVPTNLQPAP 1038
            |.|.|..:.:..|.:   :....:..|.:.|.||.:.||
 Frog   419 TDSHEKISNILNTKDIQGTECNYKTSAKKESSSLFSDSV-------------------------- 457

  Fly  1039 MLMNQSSVQRLQSSPPIAQRTMHASKHTGTPGSTPSSVANAINKTVMRARNSEAAFLAQKQQQKQ 1103
            :..::.||..:....||.:|..:..::                      :.|::.....|.::..
 Frog   458 LHASEGSVSLVPPLKPICRRECYLKEN----------------------KKSKSIIDLTKDEEND 500

  Fly  1104 HQQQQQQQQQHLQQQQKQQQAQQQFLLPRPSPGPTPGSSPAKQVPKCTTKVRAKQPPLSGATVSV 1168
            .::.......||.:                    ||.....| :.:|...:..|.|.||. ||.:
 Frog   501 CKEHNSVCLSHLTR--------------------TPDIKDIK-LEECDACLEQKNPALSD-TVKM 543

  Fly  1169 P-------ISSSSSGSELGS---YGQQQESSLAPAKPKEKAVIDLTDEDDAAAAAAARAAQAQNA 1223
            |       |.:.||..||..   :.|.:::...|.|.:|:.....||
 Frog   544 PFENKVSGICNESSAMELSPKPLHTQCKKTKTGPIKAEEQYSNKATD------------------ 590

  Fly  1224 RLRME----MLKRNAQTAAATRGGRGGGNVVRASPMQLPRVNARQIVHNNGGGQQSPLGSNVTMQ 1284
             |::|    :.:.||.....|:              .|.::.|.              |.|.:..
 Frog   591 -LKLEGKCSVTQDNASLLDTTQ--------------MLYKIKAS--------------GCNESEM 626

  Fly  1285 IRSENTPPPASRLRYSHPAPLPTSPPQPFNPSWKV-PPSRPVIRISLLDT--GIVISWTLEDSSP 1346
            .:| ||.||.:::..|:..          :.|.|: ||.:|.:|::.:..  ||.:||.:..:.|
 Frog   627 TKS-NTNPPHTQVTSSNCD----------SGSKKLQPPQKPELRLTQVQNPKGIALSWNINKTDP 680

  Fly  1347 RFAECVMYQIYAYQETINEPSTDSWRHVGDVSAMLLPMAVTLNQFQENQRYYFAVRGVDSHERFG 1411
            ..|....|.:|.::...:.... .|:.:|::.|:.||||.||.||.:...|.||:|..|...|||
 Frog   681 NCAPAESYCLYVHKVDASVKKV-LWKKIGEIKALPLPMACTLTQFVDGSTYSFALRAKDPSGRFG 744

  Fly  1412 P 1412
            |
 Frog   745 P 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wde	NP_610608.1	PTZ00121	<154..818	CDD:173412	59/356 (17%)
		DUF5585	<927..>1074	CDD:465521	23/149 (15%)
		fn3_4	1320..1418	CDD:465273	32/95 (34%)
atf7ip2	XP_012826363.1	235kDa-fam	<192..>531	CDD:130673	83/523 (16%)
		ATF7IP_BD	295..>394	CDD:465271	28/162 (17%)
		fn3_4	652..751	CDD:465273	32/95 (34%)