DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33144 and ANKIB1

DIOPT Version :9

Sequence 1:NP_001188904.1 Gene:CG33144 / 36131 FlyBaseID:FBgn0053144 Length:1102 Species:Drosophila melanogaster
Sequence 2:NP_061877.1 Gene:ANKIB1 / 54467 HGNCID:22215 Length:1089 Species:Homo sapiens


Alignment Length:317 Identity:69/317 - (21%)
Similarity:114/317 - (35%) Gaps:91/317 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   741 CCVRDGIALKRREMLASADVTP---------SVGTPATPTTAFKPFT----------------CK 780
            ||.|.|:.:.          ||         ::.:|.||.|.....|                |.
Human   280 CCQRSGVQMP----------TPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCD 334

  Fly   781 LCLIDVEDVGEAMALQQCGCQFCIECMRAYVEFEISEG-AYEISCPDATCPAQGAISLPEIANLT 844
            :|:..: .|.|......||..||..|..:::..:|.|| |:.|.||...|.....:.:  |.::.
Human   335 ICMCSI-SVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI--IESVV 396

  Fly   845 TTNLLKKHHRYRLNREIELDKTRTWCPRAGCETICTVGAAAQPGQSSVICQMDESPSTSQSYSPQ 909
            :..:.|::.::.:...:|.:....|||..||:....:                    |.|     
Human   397 SKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRL--------------------TKQ----- 436

  Fly   910 QEVAGNGSTGAAAGNGAPVLSVSVHCPSCKDEFCGLCKKAYHPNISCDEFGRRL----------- 963
                |:.::|:...:...:.:.:|.|.. ...||..|....|....|..:...|           
Human   437 ----GSNTSGSDTLSFPLLRAPAVDCGK-GHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEEL 496

  Fly   964 --IADGQDDIGIPFDNEL-----IKCCPMCAVPIEKDEGCAQMMCKRCKHVFCWYCL 1013
              :::..:|..    |.|     .|.|..|..||:|:|||..|.|.:||:.|||.||
Human   497 VGVSEAYEDAA----NCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33144NP_001188904.1 IBR 850..956 CDD:214763 17/105 (16%)
IBR <976..1014 CDD:279784 20/43 (47%)
ANKIB1NP_061877.1 ANK 1 45..74
ANK 47..194 CDD:238125
ANK repeat 47..76 CDD:293786
Ank_2 50..175 CDD:289560
ANK repeat 78..142 CDD:293786
ANK repeat 144..175 CDD:293786
ANK 2 144..173
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 281..321 10/49 (20%)
TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221 329..569 58/258 (22%)
zf-RING_2 333..379 CDD:290367 14/46 (30%)
IBR 402..475 CDD:279784 17/102 (17%)
IBR 501..552 CDD:279784 21/53 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 776..821
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 889..912
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 927..964
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1026..1089
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1815
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469819at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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