Protein Alignment CG33144 and ANKIB1

DIOPT Version :10

• Sequence 1: NP_788324.1
• Gene: CG33144 / 36131
• FlyBaseID: FBgn0053144
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: NP_061877.1
• Gene: ANKIB1 / 54467
• HGNCID: 22215
• Length: 1089
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 69/317 - (21%)
• Similarity: 114/317 - (35%)
• Gaps: 91/317 - (28%)

  Fly   741 CCVRDGIALKRREMLASADVTP---------SVGTPATPTTAFKPFT----------------CK 780
            ||.|.|:.:.          ||         ::.:|.||.|.....|                |.
Human   280 CCQRSGVQMP----------TPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCD 334

  Fly   781 LCLIDVEDVGEAMALQQCGCQFCIECMRAYVEFEISEG-AYEISCPDATCPAQGAISLPEIANLT 844
            :|:..: .|.|......||..||..|..:::..:|.|| |:.|.||...|.....:.:  |.::.
Human   335 ICMCSI-SVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDI--IESVV 396

  Fly   845 TTNLLKKHHRYRLNREIELDKTRTWCPRAGCETICTVGAAAQPGQSSVICQMDESPSTSQSYSPQ 909
            :..:.|::.::.:...:|.:....|||..||:....:                    |.|
Human   397 SKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRL--------------------TKQ----- 436

  Fly   910 QEVAGNGSTGAAAGNGAPVLSVSVHCPSCKDEFCGLCKKAYHPNISCDEFGRRL----------- 963
                |:.::|:...:...:.:.:|.|.. ...||..|....|....|..:...|
Human   437 ----GSNTSGSDTLSFPLLRAPAVDCGK-GHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEEL 496

  Fly   964 --IADGQDDIGIPFDNEL-----IKCCPMCAVPIEKDEGCAQMMCKRCKHVFCWYCL 1013
              :::..:|..    |.|     .|.|..|..||:|:|||..|.|.:||:.|||.||
Human   497 VGVSEAYEDAA----NCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33144	NP_788324.1	mRING-HC-C4C4_RBR_RNF144	777..829	CDD:438294	17/68 (25%)
		BRcat_RBR_RNF144	860..961	CDD:439010	17/100 (17%)
		Rcat_RBR_RNF144	976..1045	CDD:439013	20/43 (47%)
ANKIB1	NP_061877.1	ANKYR	<14..200	CDD:440430
		ANK 1	45..74
		ANK repeat	47..76	CDD:293786
		ANK repeat	78..142	CDD:293786
		ANK repeat	144..175	CDD:293786
		ANK 2	144..173
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..321		10/49 (20%)
		TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	329..569		58/258 (22%)
		RING-HC_RBR_ANKIB1	331..388	CDD:438430	17/57 (30%)
		BRcat_RBR_ANKIB1	409..487	CDD:439007	18/107 (17%)
		Rcat_RBR_ANKIB1	508..569	CDD:439022	20/42 (48%)
		Ariadne	584..>712	CDD:466073
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	776..821
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	889..912
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	927..964
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1026..1089