Protein Alignment CG33144 and Rnf217

DIOPT Version :10

• Sequence 1: NP_788324.1
• Gene: CG33144 / 36131
• FlyBaseID: FBgn0053144
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: NP_001139821.1
• Gene: Rnf217 / 268291
• MGIID: 3610311
• Length: 515
• Species: Mus musculus
• Alignment Length: 510
• Identity: 115/510 - (22%)
• Similarity: 176/510 - (34%)
• Gaps: 138/510 - (27%)

  Fly   555 GLSQSRSQGHSLAVHGSGIFSSGGVEQIRPL-NRLRNSVSSINGVGTCSRCSSLLSLAASGSRYS 618
            |..||...| |.....||..|:|..|..||. :|:|                      .:|.|.:
Mouse     2 GEEQSTVSG-SGGARASGGGSAGQPESPRPRGDRVR----------------------TAGPRAA 43

  Fly   619 LSNGFAPRPTSALNHLEAGWEDDQRRAQEPHIN-----VNAQIRLSG----------------GA 662
            .|:.   ||.......:.|..|  ...|||..|     ..|::.|||                ||
Mouse    44 ASSS---RPNGGGGGRDPGCVD--ASVQEPASNRAPAGQPARLPLSGPLDPQSLELQLEREAEGA 103

  Fly   663 TANSTSP--SPPSNV---TTATLHSSSANNLNQEPQ-------------QSTSTPATTPTETPGS 709
            ......|  .||..:   ..|..|...|     :||             ::.|..:.:|:|:|..
Mouse   104 GPREAPPGQQPPDGLLLDVLAQRHPPPA-----KPQVLCSVYCVESDLPEAPSAESPSPSESPPQ 163

  Fly   710 GELGPFGTNHAYPLTVSSLLSMASANQAAQACCVRDGIALKRREMLASA--DVTPSVGTP----- 767
            ..|||...:.. |...||.||:.:...:.      ||.:::....||..  .|...:|.|
Mouse   164 APLGPIPASPP-PSFPSSPLSLPADPLSP------DGGSIELEFYLAPEPFSVPGLLGAPPYSGL 221

  Fly   768 ---ATPTTAFKPFTCKLCLIDVEDVGEAMALQQCGCQFCIECMRAYVEFEISEGAYEISCPDATC 829
               ..|........|::||.|    .....|..|....|.||::.|:..::..|..||.||...|
Mouse   222 GGVGDPYAPLMVLMCRVCLED----KPIKPLPCCKKAVCEECLKIYLSSQVQLGQVEIKCPVTEC 282

  Fly   830 PAQGAISLPEIANLTTTNLLKKHHRYRLNREIELDKTRTWCPRAGCETICTVGAAAQPGQSSVIC 894
             .:.......:.|||..:.:|..:...|.|   :|.:...||:  |:...|.   .:.|..
Mouse   283 -FEFLEETTVVYNLTHEDSIKYKYFLELGR---IDSSTKPCPQ--CKHFTTF---KKKGHI---- 334

  Fly   895 QMDESPSTSQSYSPQQEVAGNGSTGAAAGNGAPVLSVSVHCPSCKDEFCGLCKKAYHPNISCDEF 959
               .:||.|:|                        ...:.||:|:..:|..|...:|..::|.|:
Mouse   335 ---PTPSRSES------------------------RYKIQCPTCQLIWCFKCHSPWHEGVNCKEY 372

  Fly   960 --GRRLIADGQDDIGIPFDNELIKCCPMCAVPIEKDEGCAQMMCKRCKHVFCWYC 1012
              |.:|:.....:  |.......:.||.|.:.|::.|||..|.|.:|...||:.|
Mouse   373 KKGDKLLRHWASE--IEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCYRC 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33144	NP_788324.1	mRING-HC-C4C4_RBR_RNF144	777..829	CDD:438294	15/51 (29%)
		BRcat_RBR_RNF144	860..961	CDD:439010	18/102 (18%)
		Rcat_RBR_RNF144	976..1045	CDD:439013	13/37 (35%)
Rnf217	NP_001139821.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..125		34/150 (23%)
		PHA03307	<25..>141	CDD:223039	30/147 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..189		12/42 (29%)
		TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	232..451		56/240 (23%)
		vRING-HC-C4C4_RBR_RNF217	234..282	CDD:438284	15/51 (29%)
		BRcat_RBR_RNF217	311..385	CDD:439003	21/112 (19%)
		Rcat_RBR_RNF217	389..456	CDD:439011	13/37 (35%)