Protein Alignment CG33144 and ARIH1

DIOPT Version :10

• Sequence 1: NP_788324.1
• Gene: CG33144 / 36131
• FlyBaseID: FBgn0053144
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: NP_005735.2
• Gene: ARIH1 / 25820
• HGNCID: 689
• Length: 557
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 60/248 - (24%)
• Similarity: 93/248 - (37%)
• Gaps: 70/248 - (28%)

  Fly   779 CKLCLIDVEDVGEAMALQQCGCQFCIECMRAYVEFEISEGAYEISCPDATCPAQGAISLPE---I 840
            |::|.::..:  ......:||.:||::|...|:..:|.|   |......:|||.|...|.:   :
Human   186 CQICYLNYPN--SYFTGLECGHKFCMQCWSEYLTTKIME---EGMGQTISCPAHGCDILVDDNTV 245

  Fly   841 ANLTTTNLLK-KHHRYRLNREIELDKTRTWCPRAGCETICTVGAAAQPGQSSVICQMDESPSTSQ 904
            ..|.|.:.:| |:.....|..:|.::...|||...|..:..|   ..|....|.|:
Human   246 MRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKV---QYPDAKPVRCK--------- 298

  Fly   905 SYSPQQEVAGNGSTGAAAGNGAPVLSVSVHCPSCKDEFCGLCKKAYHPNISCDEFGRRLIADGQD 969
                                             |..:||..|.:.:|..:.| ::.::.|....|
Human   299 ---------------------------------CGRQFCFNCGENWHDPVKC-KWLKKWIKKCDD 329

  Fly   970 DIGIPFDNEL-------IKCCPMCAVPIEKDEGCAQMMCK--RCKHVFCWYCL 1013
                  |:|.       .|.||.|.|.||||.||..|:|:  .||..|||.||
Human   330 ------DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33144	NP_788324.1	mRING-HC-C4C4_RBR_RNF144	777..829	CDD:438294	11/49 (22%)
		BRcat_RBR_RNF144	860..961	CDD:439010	15/100 (15%)
		Rcat_RBR_RNF144	976..1045	CDD:439013	22/47 (47%)
ARIH1	NP_005735.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95
		UBA-like. /evidence=ECO:0000305|PubMed:23707686	105..153
		TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	182..393		60/248 (24%)
		RING-HC_RBR_HHARI	184..242	CDD:438288	16/60 (27%)
		BRcat_RBR_HHARI-like	251..332	CDD:439004	21/132 (16%)
		Rcat_RBR_HHARI-like	336..393	CDD:439017	20/41 (49%)
		Ariadne	394..>525	CDD:466073
		Ariadne domain. /evidence=ECO:0000305|PubMed:23707686	408..557