DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33144 and ankib1

DIOPT Version :9

Sequence 1:	NP_001188904.1	Gene:	CG33144 / 36131	FlyBaseID:	FBgn0053144	Length:	1102	Species:	Drosophila melanogaster
Sequence 2:	XP_012821068.1	Gene:	ankib1 / 100145487	XenbaseID:	XB-GENE-1002083	Length:	1063	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	67/318 - (21%)
Similarity:	116/318 - (36%)	Gaps:	93/318 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   741 CCVRDGIALKRREMLASADVTP---------SVGTPATPTTAFKPFT----------------CK 780
            ||.|.|:.:.          ||         ::.:|.||.|.....|                |.
Frog   281 CCQRSGVQMP----------TPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDIDTPLCG 335

  Fly   781 LCLIDV---EDVGEAMALQQCGCQFCIECMRAYVEFEISEG-AYEISCPDATCPAQGAISLPEIA 841
            :|:.::   ||..|.    .||.:||..|..:::..:|.|| |:.|.||...|  ...:.:..|.
Frog   336 ICMCNISVFEDPVEI----PCGHEFCRVCWESFLNLKIQEGEAHNIFCPAYDC--FQLVPVDVIE 394

  Fly   842 NLTTTNLLKKHHRYRLNREIELDKTRTWCPRAGCETICTV--GAAAQPGQSSVICQMDESPSTSQ 904
            ::.:..:.|::.::.:...:|.:....|||...||....:  ......|..::...:..:|:..
Frog   395 SVVSKEMDKRYLQFDIKAFVENNTAIRWCPTPACERAVRLKKQGTNTSGSDTLTFPLLRAPAVD- 458

  Fly   905 SYSPQQEVAGNGSTGAAAGNGAPVLSVSVHCPSCKDEFCGLCKKAYHPNISCDEFGRRL--IADG 967
                    .|.|..                       ||..|....|....|:.:...|  :::.
Frog   459 --------CGKGHL-----------------------FCWECLGEAHEPCDCETWKNWLQKVSEM 492

  Fly   968 QDD--IGI--PFDNEL--------IKCCPMCAVPIEKDEGCAQMMCKRCKHVFCWYCL 1013
            :.:  :|:  .|::..        .|.|..|..||:|:|||..|.|.:||:.|||.||
Frog   493 KPEELVGVSEAFEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICL 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33144	NP_001188904.1	IBR	850..956	CDD:214763	15/107 (14%)
CG33144	NP_001188904.1	IBR	<976..1014	CDD:279784	18/46 (39%)
ankib1	XP_012821068.1	ANK repeat	47..77	CDD:293786
		Ank_2	50..176	CDD:372319
		ANK repeat	79..143	CDD:293786
		ANK repeat	145..176	CDD:293786
		RING-HC_RBR_ANKIB1	333..389	CDD:319688	18/61 (30%)
		RING-HC finger (C3HC4-type)	334..384	CDD:319688	17/53 (32%)
		IBR	403..476	CDD:366672	15/104 (14%)
		IBR	<519..553	CDD:366672	17/32 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010