DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33144 and rnf144b

DIOPT Version :9

Sequence 1:	NP_001188904.1	Gene:	CG33144 / 36131	FlyBaseID:	FBgn0053144	Length:	1102	Species:	Drosophila melanogaster
Sequence 2:	XP_031759023.1	Gene:	rnf144b / 100124330	XenbaseID:	XB-GENE-1010811	Length:	337	Species:	Xenopus tropicalis

Alignment Length:	407	Identity:	151/407 - (37%)
Similarity:	197/407 - (48%)	Gaps:	93/407 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   689 NQEPQQSTSTPATTPTETPGSGELGPFGTNHAYPLTVSSLLSMASANQAAQACCVRDGIALKRRE 753
            |:..|:|:||...:.|......|.....||            ||||.:..            ...
Frog     5 NKTSQESSSTRRRSTTILSEDLECSLSKTN------------MASAGKVC------------HHT 45

  Fly   754 MLASADVTPSVGTPATPTTAFKP-FTCKLCLIDVEDVGEAMALQQCGCQFCIECMRAYVEFEISE 817
            |||        |..:....:.:| ..|||||.: ....:..:||.|.|.||..|::.|::|.|.|
Frog    46 MLA--------GNSSPGELSLEPLILCKLCLCE-HPFDKMTSLQACSCIFCTSCLKQYIQFAIRE 101

  Fly   818 G-AYEISCPDATCPAQGAISLPEIANLTTTNLLKKHHRYRLNREIELDKTRTWCPRAGCETICTV 881
            | ...|:||:..|..||.:...||:.|.....|:.:.|.:|.||:.:|..:||||...|.|:|.|
Frog   102 GFGSPITCPNTVCTNQGILQEAEISALVPVEQLQLYQRLKLEREVHMDPCKTWCPTVDCHTVCHV 166

  Fly   882 GAAAQPGQSSVICQMDESPSTSQSYSPQQEVAGNGSTGAAAGNGAPVLSVSVHCPSCKDEFCGLC 946
                                            ..|.:|         |.|.|.|.:|..:||.:|
Frog   167 --------------------------------ETGDSG---------LPVPVDCSACLIKFCSVC 190

  Fly   947 KKAYHPNISCD--------EFGRRLIADGQDDIGIPFDNELIKCCPMCAVPIEKDEGCAQMMCKR 1003
            |..:||..||.        |.|..|..|         .:..||.||:|.:.||::|||||||||.
Frog   191 KNIWHPGQSCQVNLPIIPPEKGILLTKD---------VDACIKQCPVCRIYIERNEGCAQMMCKN 246

  Fly  1004 CKHVFCWYCLASLDDDFLLRHYDKGPCKNKLGHSRASVVWHRAQVIGIFAGFGILLLVASPLLLL 1068
            |:|.||||||.:||:|..|||||||||:||||||||||:|:|.||:||..|.|||.:|.||||||
Frog   247 CRHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGILAVVTSPLLLL 311

  Fly  1069 AAPCIICCKCRGCTGSK 1085
            |:||||||.|:.|.|.|
Frog   312 ASPCIICCVCKSCKGKK 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33144	NP_001188904.1	IBR	850..956	CDD:214763	26/105 (25%)
CG33144	NP_001188904.1	IBR	<976..1014	CDD:279784	23/37 (62%)
rnf144b	XP_031759023.1	mRING-HC-C4C4_RBR_RNF144B	62..118	CDD:319692	21/56 (38%)
		IBR	135..197	CDD:396187	25/102 (25%)
		IBR	<220..258	CDD:396187	24/37 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9166
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002315
OrthoInspector	1	1.000	-	-		otm48507
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X336
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910