DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mat1 and mnat1

DIOPT Version :9

Sequence 1:	NP_610605.1	Gene:	Mat1 / 36130	FlyBaseID:	FBgn0024956	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001006100.1	Gene:	mnat1 / 450080	ZFINID:	ZDB-GENE-041010-203	Length:	309	Species:	Danio rerio

Alignment Length:	312	Identity:	167/312 - (53%)
Similarity:	228/312 - (73%)	Gaps:	8/312 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDDQACPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFLKGSGACPECMVPLRRNNFRVQLFED 65
            ||||.|||||||||||||||||||||||||||||||:||::|||.|.:|..|||::|||||||||
Zfish     1 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDMLFVRGSGNCVQCDTPLRKSNFRVQLFED 65

  Fly    66 PMVEKEVDIRRRILRDYNKREEDFASLAEYNDYLEEIEDIVYNLCNNIDIIETNKRIEAYKRDNR 130
            |.:.|||:||:::|:.|||||.||:||.|||||||::||||:||.||:|:..|.:::|.|:|||:
Zfish    66 PAIGKEVEIRKKVLKIYNKREFDFSSLTEYNDYLEQVEDIVFNLANNMDVEMTKQKMEQYQRDNK 130

  Fly   131 EVIQRNKTRVGRDEYALEEMLELEKVQEEARRKELEELENEHKKKKARDKQALIEELMYSGKDAA 195
            :||||||.::.|::..|||:|..|:...|.||.|..:.|....:.|.::||||::||..|...||
Zfish   131 DVIQRNKAKLTREQEELEELLLQEQQDSELRRLETLQEEQRQLQAKRKNKQALLDELENSKLPAA 195

  Fly   196 QIVTEFAEKA---EKQREEEKQLPPPKPANEFSTGIKFGQTADPSLLPVPKSEEGPLFVYEPLVP 257
            .::.:..::|   |.|.|::||  ..||.|.|||||..|||.  ||..|.:.|| .|:.|:||..
Zfish   196 VLLAQHKDRAAHLETQIEKQKQ--NVKPTNIFSTGIMMGQTV--SLASVSRVEE-VLYCYQPLYI 255

  Fly   258 FSEGPAMPPTNEIVSRGYIAHIRAETPQENAGGFTSALACERALQEALQGLY 309
            .:.||.:|..:::..:|::.|:||.:.|:.|||:||.|||.||:|:|..||:
Zfish   256 DTYGPPVPELDQLGRKGFLNHVRAASLQDQAGGYTSGLACHRAIQDAFSGLF 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mat1	NP_610605.1	cdk7	1..313	CDD:129661	167/312 (54%)
		RING	3..47	CDD:302633	38/43 (88%)
		CDC37_N	66..175	CDD:296150	55/108 (51%)
		Seryl_tRNA_N	127..215	CDD:299883	35/90 (39%)
mnat1	NP_001006100.1	cdk7	1..307	CDD:129661	166/310 (54%)
		RING	3..46	CDD:302633	38/42 (90%)
		ATP-synt_B	<166..>218	CDD:304375	17/53 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595527
Domainoid	1	1.000	188	1.000	Domainoid score	I3256
eggNOG	1	0.900	-	-		E1_COG5220
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1821
Inparanoid	1	1.050	335	1.000	Inparanoid score	I2389
OMA	1	1.010	-	-		QHG55364
OrthoDB	1	1.010	-	-		D1454155at2759
OrthoFinder	1	1.000	-	-		FOG0005635
OrthoInspector	1	1.000	-	-		oto38834
orthoMCL	1	0.900	-	-		OOG6_103797
Panther	1	1.100	-	-	LDO	PTHR12683
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1502
SonicParanoid	1	1.000	-	-		X5285
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800