DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12338 and dao.2

DIOPT Version :9

Sequence 1:	NP_001286292.1	Gene:	CG12338 / 36128	FlyBaseID:	FBgn0033543	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_999897.1	Gene:	dao.2 / 405800	ZFINID:	ZDB-GENE-040426-2634	Length:	348	Species:	Danio rerio

Alignment Length:	349	Identity:	118/349 - (33%)
Similarity:	184/349 - (52%)	Gaps:	27/349 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLGSGIIGLTTALELQKEFPTARVS-----VIADRFNEDTVSYVAAGIFRPGTSFMGPTQKITQQ 64
            ::|:|:|||:||..:.:.| .:|||     |.||.|...|.|..|||:::|.....|..::  .|
Zfish     5 IIGAGVIGLSTAQSIYQHF-HSRVSPLTIEVYADIFTPLTTSDGAAGLWQPYLYDKGNVKE--TQ 66

  Fly    65 WMTDAFNYWDELRRSKEAPLAGVCQLSGYIYSRTSPSIVRNHFIEKLLPVYRRATEEELRLCNGG 129
            |..|.|||......|.::...|:...||  |:..:..:....|.:.:|. :|:.::.||.:. .|
Zfish    67 WNKDTFNYLLSFINSPDSVKMGIFLQSG--YNLCAEPMPEPSFKQAVLG-FRQLSKRELEMF-PG 127

  Fly   130 WKYGSFFTTCLTESRLFLPYATKKFLENGGEVVRQHVNSFFEVPQN-IDLLLNCTGMGAKELCGD 193
            :.:|.|.|..:.|.:.:||:......:.|....::.::||.|:..: .|:::||:|:.:.:|..|
Zfish   128 YSFGWFNTALMIEGKTYLPWLMNWLKQRGVTFFQRTIDSFKELSDSGADMIINCSGVRSGDLQPD 192

  Fly   194 QHLVPIRGQVLKVRAPWVK------TAFYGDYDT-YVLPGFETVTLGGCRQFDSYNTEWCKYDSM 251
            ..|.|.|||::||.|||:|      .:..|.||: |::||...||:||..|..::|......|..
Zfish   193 PELQPARGQIIKVDAPWLKHWVITHDSTSGVYDSPYIIPGSRLVTVGGVFQVGNWNRMNSSVDHK 257

  Fly   252 AIRERCYDLLPSLRKAEIVRECVGLRPHRSVVRVEPELITNPEGRRLKVVHNYGHGGYGVTTAPG 316
            .|.|....|.|||:.|.||.:..||||.||.||:|.|.|.: .|...:|:|||||||:|:|...|
Zfish   258 GIWEAACKLEPSLQHARIVEDWTGLRPARSKVRLEREAIRS-GGHSFEVIHNYGHGGFGLTIHRG 321

  Fly   317 TAMYAVRLV------RDLLAGNSK 334
            .|..|.||.      :.||...:|
Zfish   322 CAEEAARLFGQFLEQKGLLTAQAK 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12338	NP_001286292.1	DAO	5..324	CDD:279590	113/331 (34%)
dao.2	NP_999897.1	DAO	2..329	CDD:279590	113/331 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595846
Domainoid	1	1.000	198	1.000	Domainoid score	I3027
eggNOG	1	0.900	-	-		E1_COG0665
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63703
OrthoDB	1	1.010	-	-		D1363414at2759
OrthoFinder	1	1.000	-	-		FOG0001083
OrthoInspector	1	1.000	-	-		otm24661
orthoMCL	1	0.900	-	-		OOG6_100720
Panther	1	1.100	-	-	O	PTHR11530
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R881
SonicParanoid	1	1.000	-	-		X916
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.790