DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12338 and dao.3

DIOPT Version :9

Sequence 1:	NP_001286292.1	Gene:	CG12338 / 36128	FlyBaseID:	FBgn0033543	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_991257.1	Gene:	dao.3 / 402994	ZFINID:	ZDB-GENE-040426-1894	Length:	353	Species:	Danio rerio

Alignment Length:	340	Identity:	117/340 - (34%)
Similarity:	178/340 - (52%)	Gaps:	26/340 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VLGSGIIGLTTALELQKEFPTARVS-----VIADRFNEDTVSYVAAGIFRPGTSFMGPTQKITQQ 64
            ::|:|:|||:||..:.:.| .:|||     |.||.|...|.|..|||:::|.....|..::  .|
Zfish     5 IIGAGVIGLSTAQSIYQHF-HSRVSPLTIEVYADFFTPLTTSDGAAGLWQPYLYDKGIVKE--TQ 66

  Fly    65 WMTDAFNYWDELRRSKEAPLAGVCQLSGY-IYSRTS--PSIVRNHFIEKLLPVYRRATEEELRLC 126
            |..:.|:|......|.::...|:...||| :.:.|:  ||     |.:.:|. :|:.|..||.:.
Zfish    67 WNKETFDYLLSFINSPDSIKMGIFLQSGYNLCAETAADPS-----FKDTVLG-FRQLTSRELEMF 125

  Fly   127 NGGWKYGSFFTTCLTESRLFLPYATKKFLENGGEVVRQHVNSFFEVPQ-NIDLLLNCTGMGAKEL 190
             .|:.:|.|.|:.:.|.:.:||:......|...:..::.::||.|:.. ..|:::||:|:.:.||
Zfish   126 -PGYSFGWFNTSIMIEGKTYLPWLMDWLKERNVKFYQRKIDSFKELSACGADVIINCSGVRSGEL 189

  Fly   191 CGDQHLVPIRGQVLKVRAPWVK----TAFYGD--YDTYVLPGFETVTLGGCRQFDSYNTEWCKYD 249
            ..|..|.|.|||::||.|||:|    |..:..  ...|::||...||:||..|..::|......|
Zfish   190 QPDPELQPARGQIIKVDAPWIKHWISTHNFSSRGNSAYIIPGSRLVTVGGVFQVGNWNRLNSSVD 254

  Fly   250 SMAIRERCYDLLPSLRKAEIVRECVGLRPHRSVVRVEPELITNPEGRRLKVVHNYGHGGYGVTTA 314
            ...|.|....|.|||:.|.||.:..||||.||.||:|.|.| ...|...:|:|||||||:|:|..
Zfish   255 HKQIWEAACKLEPSLQHARIVEDWTGLRPARSKVRLERESI-RCGGHSFEVIHNYGHGGFGLTIH 318

  Fly   315 PGTAMYAVRLVRDLL 329
            .|.|..|.||....|
Zfish   319 RGCAEEAARLFGQFL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12338	NP_001286292.1	DAO	5..324	CDD:279590	114/333 (34%)
dao.3	NP_991257.1	DAO	2..328	CDD:307432	114/333 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595847
Domainoid	1	1.000	198	1.000	Domainoid score	I3027
eggNOG	1	0.900	-	-		E1_COG0665
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3708
OMA	1	1.010	-	-		QHG63703
OrthoDB	1	1.010	-	-		D1363414at2759
OrthoFinder	1	1.000	-	-		FOG0001083
OrthoInspector	1	1.000	-	-		otm24661
orthoMCL	1	0.900	-	-		OOG6_100720
Panther	1	1.100	-	-	O	PTHR11530
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R881
SonicParanoid	1	1.000	-	-		X916
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.840