Protein Alignment Rab3 and RAB3D

DIOPT Version :9

• Sequence 1: NP_001356961.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_004274.1
• Gene: RAB3D / 9545
• HGNCID: 9779
• Length: 219
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 165/221 - (74%)
• Similarity: 189/221 - (85%)
• Gaps: 3/221 - (1%)

  Fly     1 MASGGDPK-WQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVF 64
            |||.||.: ..:||||||||||||||:|||||||||||||||||||||.|||||||||||||||:
Human     1 MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVY 65

  Fly    65 RHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQV 129
            |||||:|||||||||||||||||||||||||||:||||:.|::||.:||||.|||||||||||||
Human    66 RHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQV 130

  Fly   130 ILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADP 194
            ||||||||:||:||:..|.||:|||.||.||||.|||||:|||.|||||||:||:||:|||:...
Human   131 ILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSS 195

  Fly   195 TLVGGGQKGQRLTDQPQGTPNANCNC 220
            : .|...||..:.|.|...| ::|:|
Human   196 S-SGSNGKGPAVGDAPAPQP-SSCSC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	138/163 (85%)
RAB3D	NP_004274.1	Rab3	22..186	CDD:206657	138/163 (85%)
		Effector region. /evidence=ECO:0000250	51..59		7/7 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..219		9/30 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	292	1.000	Domainoid score	I1515
eggNOG	1	0.900	-	-		E1_KOG0093
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S282
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1218073at2759
OrthoFinder	1	1.000	-	-		FOG0000908
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2742
SonicParanoid	1	1.000	-	-		X578
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.860