Protein Alignment Rab3 and RAB3D

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_004274.1
• Gene: RAB3D / 9545
• HGNCID: 9779
• Length: 219
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 165/221 - (74%)
• Similarity: 189/221 - (85%)
• Gaps: 3/221 - (1%)

  Fly     1 MASGGDPK-WQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVF 64
            |||.||.: ..:||||||||||||||:|||||||||||||||||||||.|||||||||||||||:
Human     1 MASAGDTQAGPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVY 65

  Fly    65 RHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQV 129
            |||||:|||||||||||||||||||||||||||:||||:.|::||.:||||.|||||||||||||
Human    66 RHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQV 130

  Fly   130 ILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADP 194
            ||||||||:||:||:..|.||:|||.||.||||.|||||:|||.|||||||:||:||:|||:...
Human   131 ILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSS 195

  Fly   195 TLVGGGQKGQRLTDQPQGTPNANCNC 220
            : .|...||..:.|.|...| ::|:|
Human   196 S-SGSNGKGPAVGDAPAPQP-SSCSC 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	138/163 (85%)
RAB3D	NP_004274.1	Rab3	22..186	CDD:206657	138/163 (85%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		7/8 (88%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		15/15 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..219		9/30 (30%)