DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3 and SEC4

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_116650.1	Gene:	SEC4 / 850543	SGDID:	S000001889	Length:	215	Species:	Saccharomyces cerevisiae

Alignment Length:	219	Identity:	99/219 - (45%)
Similarity:	148/219 - (67%)	Gaps:	15/219 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRH 66
            ||.|:.|        ::|.:.|:|:||:|.|||:..|.|:.:|.|..:|::|:|||||:|||..:
Yeast     9 ASSGNGK--------SYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDIN 65

  Fly    67 DKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVIL 131
            .|:||||:||||||||:|||||||||||||.||:||||:|.:|.:::.|...:..::.|.||::|
Yeast    66 GKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLL 130

  Fly   132 VGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTL 196
            ||||.||| .||::.::|..||.:||:.|.|:|||.:.||..:|..|..:|    .|.:|::..:
Yeast   131 VGNKSDME-TRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLI----QEKIDSNKLV 190

  Fly   197 -VGGGQKGQRLTDQPQG-TPNANC 218
             ||.|::|....:...| :..:||
Yeast   191 GVGNGKEGNISINSGSGNSSKSNC 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	85/163 (52%)
SEC4	NP_116650.1	Rab8_Rab10_Rab13_like	18..183	CDD:206659	86/169 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010