Protein Alignment Rab3 and RAB5C

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001238968.1
• Gene: RAB5C / 5878
• HGNCID: 9785
• Length: 249
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 76/220 - (34%)
• Similarity: 114/220 - (51%)
• Gaps: 7/220 - (3%)

  Fly     1 MASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFR 65
            ||..|........|..|....|||:::|.|:|||:|.:.|:....|.....||:|..|..:||..
Human    34 MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCL 98

  Fly    66 HDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVI 130
            .|..||.:||||||||||.::...|||||...|::||:||.|:|...::||.:::..:..|..:.
Human    99 DDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIA 163

  Fly   131 LVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPT 195
            |.|||.|:..:|.:.|:..:..||...:.|.|||||..:||..:|.    .|..|:.::...:.|
Human   164 LAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFM----AIAKKLPKNEPQNAT 224

  Fly   196 LVGGGQKGQRLTDQPQGTPNANCNC 220
            ...|..:|   .|..:..|.:...|
Human   225 GAPGRNRG---VDLQENNPASRSQC 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	64/163 (39%)
RAB5C	NP_001238968.1	Rab5_related	54..216	CDD:206653	65/165 (39%)