Protein Alignment Rab3 and RAB13

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_002861.1
• Gene: RAB13 / 5872
• HGNCID: 9762
• Length: 203
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 93/202 - (46%)
• Similarity: 138/202 - (68%)
• Gaps: 13/202 - (6%)

  Fly    18 FDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQER 82
            :|::||||:||:|.||||..:.|:|:|:|.:.::||:|||||::||....|::|||:||||||||
Human     5 YDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 69

  Fly    83 YRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFE 147
            ::||||||||||||.||:||:|:|.||.::|:|:..||..:....:.:|:|||||||.:|.:..|
Human    70 FKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKE 134

  Fly   148 RGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQG 212
            :..:||.:.|:.|||||||.::||            |:...||..|..|..||::... .::|..
Human   135 QADKLAREHGIRFFETSAKSSMNV------------DEAFSSLARDILLKSGGRRSGN-GNKPPS 186

  Fly   213 TPNANCN 219
            |....|:
Human   187 TDLKTCD 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	82/163 (50%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	87/177 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		14/16 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..203		5/22 (23%)