DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab3 and RAB3B

DIOPT Version :9

Sequence 1:NP_001356961.1 Gene:Rab3 / 36127 FlyBaseID:FBgn0005586 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_002858.2 Gene:RAB3B / 5865 HGNCID:9778 Length:219 Species:Homo sapiens


Alignment Length:223 Identity:170/223 - (76%)
Similarity:193/223 - (86%) Gaps:7/223 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MASGGDPK-WQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVF 64
            |||..|.| ..|||:||||||||||||||||||||||||||||||:||.|||||||||||||||:
Human     1 MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVY 65

  Fly    65 RHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQV 129
            ||:|||||||||||||||||||||||||||||||||||:|||:|||:||||.|||||||||||||
Human    66 RHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQV 130

  Fly   130 ILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADP 194
            ||||||||||::||:..|:|:.||:|||.:|||.|||||::|:..||||||.||||||:|||.||
Human   131 ILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDP 195

  Fly   195 TLVGGGQKGQRLTDQPQGTP--NANCNC 220
            ::: |..|..||:|.|   |  ..||:|
Human   196 SML-GSSKNTRLSDTP---PLLQQNCSC 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab3NP_001356961.1 Rab3 21..185 CDD:206657 137/163 (84%)
RAB3BNP_002858.2 Rab3 22..186 CDD:206657 137/163 (84%)
RAB 23..183 CDD:197555 134/159 (84%)
Effector region. /evidence=ECO:0000250 51..59 7/7 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0093
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 351 1.000 Inparanoid score I2274
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D503770at33208
OrthoFinder 1 1.000 - - FOG0000908
OrthoInspector 1 1.000 - - otm41033
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR47980
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2742
SonicParanoid 1 1.000 - - X578
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1110.960

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