DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3 and rab3da

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001139069.1	Gene:	rab3da / 567288	ZFINID:	ZDB-GENE-080722-14	Length:	223	Species:	Danio rerio

Alignment Length:	224	Identity:	168/224 - (75%)
Similarity:	192/224 - (85%)	Gaps:	5/224 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASGGDPKW----QKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVK 61
            |||..|.:.    |||.||||||||||||||||||||||||||||||||||||||||||||||||
Zfish     1 MASANDTRHQTQVQKDVADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVK 65

  Fly    62 TVFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDN 126
            ||:|::||||||||||||||||||||||||||||||:||||:||:|||.:||||.||||||||||
Zfish    66 TVYRNEKRVKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDITNQDSFYAVQDWATQIKTYSWDN 130

  Fly   127 AQVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLD 191
            |||||||||||:||.|:::.|.|::||::||.:|||.|||:|:|||.|||||||||||||:||||
Zfish   131 AQVILVGNKCDLEDDRLVAREDGQRLANELGFQFFEASAKDNINVKQVFERLVDIICDKMNESLD 195

  Fly   192 ADPTLVGGGQKGQRLTDQPQGTPNANCNC 220
            .||::: ..|||..|.|.|....:..|.|
Zfish   196 TDPSIL-TNQKGPSLQDTPPDGQSGGCGC 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	137/163 (84%)
rab3da	NP_001139069.1	Rab3	25..189	CDD:206657	137/163 (84%)
rab3da	NP_001139069.1	RAB	26..186	CDD:197555	133/159 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1218073at2759
OrthoFinder	1	1.000	-	-		FOG0000908
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X578
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.020