DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab3 and rab3aa

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001003419.1	Gene:	rab3aa / 445024	ZFINID:	ZDB-GENE-040801-2	Length:	220	Species:	Danio rerio

Alignment Length:	222	Identity:	167/222 - (75%)
Similarity:	200/222 - (90%)	Gaps:	4/222 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASGGDPKW-QKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVF 64
            |||..|.:: |||:|:||||||||:|||||||||||||||||||||||.||||||||||||||::
Zfish     1 MASANDARYGQKDSAEQNFDYMFKVLIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIY 65

  Fly    65 RHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQV 129
            |:|||:||||||||||||||||||||||||||||||||:|||||||:||||.|||||||||||||
Zfish    66 RNDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEDSFNAVQDWSTQIKTYSWDNAQV 130

  Fly   130 ILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLD-AD 193
            :||||||||||:||::.:|||||::|||.||||.|||:|:|||..||||||:||::|||:|: ||
Zfish   131 LLVGNKCDMEDERVVAGQRGRQLSEQLGFEFFEASAKDNINVKQTFERLVDVICERMSENLESAD 195

  Fly   194 PTLVGGGQKGQRLTDQPQGTPNANCNC 220
            |::. |.:.|..|::|||.: :.:|.|
Zfish   196 PSMT-GNKLGPELSEQPQRS-HKDCAC 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	139/163 (85%)
rab3aa	NP_001003419.1	Rab3	22..186	CDD:206657	139/163 (85%)
rab3aa	NP_001003419.1	RAB	23..183	CDD:197555	136/159 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	289	1.000	Domainoid score	I1520
eggNOG	1	0.900	-	-		E1_KOG0093
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	346	1.000	Inparanoid score	I2285
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1218073at2759
OrthoFinder	1	1.000	-	-		FOG0000908
OrthoInspector	1	1.000	-	-		otm25714
orthoMCL	1	0.900	-	-		OOG6_105135
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X578
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.830