DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3 and rab3c

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	XP_005166882.1	Gene:	rab3c / 436803	ZFINID:	ZDB-GENE-040718-263	Length:	224	Species:	Danio rerio

Alignment Length:	220	Identity:	165/220 - (75%)
Similarity:	192/220 - (87%)	Gaps:	2/220 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFR 65
            ||:..|.| ||:.:||||||||||||||||||||||||||||||:||||||||||||||||||::
Zfish     7 MAATQDNK-QKENSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTSAFVSTVGIDFKVKTVYK 70

  Fly    66 HDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVI 130
            :|||:||||||||||||||||||||||||||||||||:|||:||.:||||.||||||||||||||
Zfish    71 NDKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFAAVQDWATQIKTYSWDNAQVI 135

  Fly   131 LVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPT 195
            |.|||||||::|::|.:.||.||:|||.||||||||:|:|||..|:|||||||||||::|:|||.
Zfish   136 LAGNKCDMEEERIVSVDSGRLLAEQLGFEFFETSAKDNINVKQTFDRLVDIICDKMSDTLEADPA 200

  Fly   196 LVGGGQKGQRLTDQPQGTPNANCNC 220
             ..||....|||:.|.....::|:|
Zfish   201 -AAGGTPSARLTETPAPPQPSDCSC 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	137/163 (84%)
rab3c	XP_005166882.1	Rab3	26..190	CDD:206657	137/163 (84%)
rab3c	XP_005166882.1	RAB	27..187	CDD:197555	133/159 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0093
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23420
Inparanoid	1	1.050	346	1.000	Inparanoid score	I2285
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1218073at2759
OrthoFinder	1	1.000	-	-		FOG0000908
OrthoInspector	1	1.000	-	-		otm25191
orthoMCL	1	0.900	-	-		OOG6_105135
Panther	1	1.100	-	-	LDO	PTHR47980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2742
SonicParanoid	1	1.000	-	-		X578
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.860