Protein Alignment Rab3 and RAB37

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001006639.1
• Gene: RAB37 / 326624
• HGNCID: 30268
• Length: 223
• Species: Homo sapiens
• Alignment Length: 172
• Identity: 78/172 - (45%)
• Similarity: 116/172 - (67%)
• Gaps: 1/172 - (0%)

  Fly     5 GDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTS-AFVSTVGIDFKVKTVFRHDK 68
            |:...:......::|...|::::|::.||||.||.::.|.:|.| .|::||||||:.|.|.....
Human    13 GEAPERSPPCSPSYDLTGKVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGV 77

  Fly    69 RVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVG 133
            ||||||||||||||:|::|.||||.|...:|:||:||:.||::::.|:|:|..|:..:..::|:|
Human    78 RVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLG 142

  Fly   134 NKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVF 175
            ||.||..:|||..|.|..||.:.||.|.|||||..:||:..|
Human   143 NKADMSSERVIRSEDGETLAREYGVPFLETSAKTGMNVELAF 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	76/156 (49%)
RAB37	NP_001006639.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		1/9 (11%)
		Rab26	31..220	CDD:206695	76/154 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	52..67		7/14 (50%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	85..102		12/16 (75%)