DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3 and Rab40

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_727611.1	Gene:	Rab40 / 32195	FlyBaseID:	FBgn0030391	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	59/170 - (34%)
Similarity:	95/170 - (55%)	Gaps:	13/170 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVS----------TVGIDFKVKTVFRHDKRV 70
            :::||:.|:|::|:|.|||...|....|.|..|.|.|          ||.  :|..|:....|||
  Fly     6 KDYDYLLKVLLVGDSDVGKHEILSNLEDPSTESPFCSGNDCTSHILQTVA--YKTTTILLEGKRV 68

  Fly    71 KLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNK 135
            |||:|||:||.|:.||..:|.|||.|.||:||:||:.||:.:..|:.::..:: .....:||||:
  Fly    69 KLQLWDTSGQGRFCTIIRSYSRGAQGIILVYDITNKWSFDGIDRWLKEVDEHA-PGIPKVLVGNR 132

  Fly   136 CDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVF 175
            ..:..:|.::.::....|.:..:..||.|...|.|::..|
  Fly   133 LHLAFKRQVAAKQAETYASRNNMSCFEISPLCNFNIRESF 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	57/165 (35%)
Rab40	NP_727611.1	P-loop_NTPase	6..265	CDD:304359	59/170 (35%)
		RAB	12..182	CDD:197555	57/164 (35%)
		SOCS	192..234	CDD:295349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47980
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100