Protein Alignment Rab3 and RAB30

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_055303.2
• Gene: RAB30 / 27314
• HGNCID: 9770
• Length: 203
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 77/198 - (38%)
• Similarity: 127/198 - (64%)
• Gaps: 9/198 - (4%)

  Fly    16 QNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQ 80
            :::|::||:::|||:.||||..:.|:....|.....:|:|:||.:|||..:.::|||||||||||
Human     4 EDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQ 68

  Fly    81 ERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVIS 145
            ||:|:||.:|||.|...||.||:|.|:||..:.:|:.:|:.|:.:....:|||||.|:.::|.:|
Human    69 ERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAERREVS 133

  Fly   146 FERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESL------DADPTLVGGGQKGQ 204
            .:|..:.::...:.:.||||||:.||:.:|   :|:.|..:||:.      :....|.|.|:...
Human   134 QQRAEEFSEAQDMYYLETSAKESDNVEKLF---LDLACRLISEARQNTLVNNVSSPLPGEGKSIS 195

  Fly   205 RLT 207
            .||
Human   196 YLT 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	69/163 (42%)
RAB30	NP_055303.2	Rab30	3..171	CDD:133314	70/169 (41%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	36..44		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	67..83		10/15 (67%)