DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3 and rab-10

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_491857.1	Gene:	rab-10 / 266836	WormBaseID:	WBGene00004273	Length:	201	Species:	Caenorhabditis elegans

Alignment Length:	178	Identity:	92/178 - (51%)
Similarity:	132/178 - (74%)	Gaps:	0/178 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTA 78
            |.:.:|.:||||:||:|.||||..|:|::||:|.:.|:||:|||||:||:....|::||||||||
Worm     2 ARRPYDMLFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDTA 66

  Fly    79 GQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRV 143
            ||||:.||||:|||||||.:|:||:||..||:::..|:..|..::.::...:::||||||.|:||
Worm    67 GQERFHTITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHASEDVVKMILGNKCDMSDRRV 131

  Fly   144 ISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLD 191
            :|.|||.::|...|:.|.|||||.||:|...|..|.:.|..||.:|.|
Worm   132 VSRERGEKIAQDHGISFHETSAKLNVHVDTAFYDLAEAILAKMPDSTD 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	86/163 (53%)
rab-10	NP_491857.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	87/165 (53%)
rab-10	NP_491857.1	RAB	10..173	CDD:197555	86/162 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910