Protein Alignment Rab3 and RAB26

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_055168.2
• Gene: RAB26 / 25837
• HGNCID: 14259
• Length: 256
• Species: Homo sapiens
• Alignment Length: 159
• Identity: 75/159 - (47%)
• Similarity: 110/159 - (69%)
• Gaps: 1/159 - (0%)

  Fly    18 FDYMFKLLIIGNSSVGKTSFLFRYADDSF-TSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQE 81
            :|..||::::|:|.||||..|.|:.|.:| ...|:|||||||:.|.:.....:||||:|||||||
Human    60 YDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAGQE 124

  Fly    82 RYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISF 146
            |:|::|.||||.|...:|:|||||:.||:::|.|:|:|..|:..:..::|:|||.|...:||:..
Human   125 RFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSAHERVVKR 189

  Fly   147 ERGRQLADQLGVEFFETSAKENVNVKAVF 175
            |.|.:||.:.|:.|.|||||..:||...|
Human   190 EDGEKLAKEYGLPFMETSAKTGLNVDLAF 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	74/156 (47%)
RAB26	NP_055168.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..51
		Rab26	64..254	CDD:206695	74/155 (48%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	86..101		7/14 (50%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	119..136		12/16 (75%)