Protein Alignment Rab3 and Rab12

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_037149.1
• Gene: Rab12 / 25530
• RGDID: 3527
• Length: 243
• Species: Rattus norvegicus
• Alignment Length: 229
• Identity: 95/229 - (41%)
• Similarity: 140/229 - (61%)
• Gaps: 23/229 - (10%)

  Fly     3 SGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHD 67
            |||..:.:|. ..:..|:..:::|||:..|||||.:.|:.||:|..|..||||:|||:|||....
  Rat    24 SGGQARRRKQ-PPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRG 87

  Fly    68 KRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILV 132
            |:::|||||||||||:.:||:||||.|.|.||:||:|.:::|:.:..|:..|..|:.::|:::||
  Rat    88 KKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLV 152

  Fly   133 GNKCDMEDQRVISFERGRQLADQL-GVEFFETSAKENVNVKAVFERLVDIICDKM------SE-- 188
            |||.|.|..|.||.::|.:.|.|: |:.|.|.|||:|.||..:|.:|||.|..||      ||
  Rat   153 GNKLDCETDREISRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDVLRSELS 217

  Fly   189 ----SLDADPTLVGGGQKGQRLTDQPQGTPNANC 218
                ||..:|.:.         .:.|...|:..|
  Rat   218 NSILSLQPEPEIP---------PELPPPRPHVRC 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	80/164 (49%)
Rab12	NP_037149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		4/12 (33%)
		Rab12	42..243	CDD:206699	90/210 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	64..78		7/13 (54%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	96..113		12/16 (75%)