Protein Alignment Rab3 and RAB21

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_055814.1
• Gene: RAB21 / 23011
• HGNCID: 18263
• Length: 225
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 81/226 - (35%)
• Similarity: 122/226 - (53%)
• Gaps: 17/226 - (7%)

  Fly     2 ASGGDPKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRH 66
            |.||.    ..||.....|.||::::|...|||||.:.||.::.|....::|:...|..|.:...
Human     4 AGGGG----GGAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIG 64

  Fly    67 DKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVIL 131
            .|||.|.|||||||||:..:...|||.:.|.||:||:|:||||..|::||.:::....:...:.:
Human    65 GKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCI 129

  Fly   132 VGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTL 196
            ||||.|:|.:|.:|.:.....|:.:|.:.:.||||:|   |.:.|..:| :|.:|.|:...|...
Human   130 VGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQN---KGIEELFLD-LCKRMIETAQVDERA 190

  Fly   197 VGGG--QKG------QRLTDQPQG-TPNANC 218
            .|.|  |.|      |.:.|:||. |....|
Human   191 KGNGSSQPGTARRGVQIIDDEPQAQTSGGGC 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	62/163 (38%)
RAB21	NP_055814.1	Rab21	20..181	CDD:133323	62/164 (38%)