Protein Alignment Rab3 and RAB18

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 85/236 - (36%)
• Similarity: 122/236 - (51%)
• Gaps: 41/236 - (17%)

  Fly    15 DQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIW---- 75
            |::.....|:||||.|.|||:|.|.|:.||:|.....:|:|:||||||:.....:.||.||
Human     2 DEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTLH 66

  Fly    76 -------------------------DTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDW 115
                                     |||||||:||:|.:|||||.|.||:||||..|:|..:.:|
Human    67 QQTANFFLKSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNW 131

  Fly   116 VTQIKTYSWDNAQV-ILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLV 179
            :.:::||...|..| :|||||.|.|: |.:....|.:.|.:..:.|.|.|||....|:..||.||
Human   132 LNELETYCTRNDIVNMLVGNKIDKEN-REVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELV 195

  Fly   180 DIICDK--MSESLDADPTLVGGGQKGQRLTDQPQGTPNANC 218
            :.|...  :.||.:.:        ||.:|:.:.:|.....|
Human   196 EKIIQTPGLWESENQN--------KGVKLSHREEGQGGGAC 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	77/193 (40%)
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	76/189 (40%)