Protein Alignment Rab3 and Rab6a

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_077249.1
• Gene: Rab6a / 19346
• MGIID: 894313
• Length: 208
• Species: Mus musculus
• Alignment Length: 231
• Identity: 83/231 - (35%)
• Similarity: 129/231 - (55%)
• Gaps: 34/231 - (14%)

  Fly     1 MASGGD---PKWQKDAADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKT 62
            |::|||   |..:           |||:.:|..||||||.:.|:..|||.:.:.:|:||||..||
Mouse     1 MSAGGDFGNPLRK-----------FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKT 54

  Fly    63 VFRHDKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNA 127
            ::..|:.|:||:||||||||:|::..:|.|.:...:::||:||.:||.....|:..::|....:.
Mouse    55 MYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDV 119

  Fly   128 QVILVGNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERL------VDIICDKM 186
            .::|||||.|:.|:|.:|.|.|.:.|.:|.|.|.|||||...|||.:|.|:      ::...|:.
Mouse   120 IIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRS 184

  Fly   187 SESLDADPTLVGGGQKGQRLTDQPQGTP--NANCNC 220
            .|.: .|..|           ::||..|  ...|:|
Mouse   185 REDM-IDIKL-----------EKPQEQPVNEGGCSC 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	69/169 (41%)
Rab6a	NP_077249.1	Rab6	14..174	CDD:206654	69/159 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20340	32..50		7/17 (41%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20340	69..88		9/18 (50%)