DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3 and Rab10

DIOPT Version :9

Sequence 1:	NP_001356961.1	Gene:	Rab3 / 36127	FlyBaseID:	FBgn0005586	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_057885.1	Gene:	Rab10 / 19325	MGIID:	105066	Length:	200	Species:	Mus musculus

Alignment Length:	196	Identity:	97/196 - (49%)
Similarity:	139/196 - (70%)	Gaps:	9/196 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTA 78
            |.:.:|.:||||:||:|.||||..|||::||:|.:.|:||:|||||:|||....|::||||||||
Mouse     2 AKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTA 66

  Fly    79 GQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRV 143
            ||||:.||||:|||||||.:|:||:||..||.::..|:..|..::.::.:.:|:||||||:|:||
Mouse    67 GQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRV 131

  Fly   144 ISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKM------SESLDADPTLVGGGQK 202
            :...:|.|:|.:.|:.|||||||.|:|::..|..|.:.|..|.      ||::|...   |||..
Mouse   132 VPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISS---GGGVT 193

  Fly   203 G 203
            |
Mouse   194 G 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_001356961.1	Rab3	21..185	CDD:206657	87/163 (53%)
Rab10	NP_057885.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	88/165 (53%)
Rab10	NP_057885.1	Effector region. /evidence=ECO:0000250	38..46		5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910