Protein Alignment Rab3 and Rab27a

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_076124.1
• Gene: Rab27a / 11891
• MGIID: 1861441
• Length: 221
• Species: Mus musculus
• Alignment Length: 223
• Identity: 90/223 - (40%)
• Similarity: 144/223 - (64%)
• Gaps: 19/223 - (8%)

  Fly    14 ADQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVK-TVFR---------HDK 68
            :|.::||:.|.|.:|:|.|||||.|::|.|..|.|.|::||||||:.| .|:|         ..:
Mouse     2 SDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGAVGRGQ 66

  Fly    69 RVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSW-DNAQVILV 132
            |:.||:||||||||:|::|||::|.||||:|::|:|||.||.:|::|::|::.::: :|..::|.
Mouse    67 RIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLC 131

  Fly   133 GNKCDMEDQRVISFERGRQLADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDAD--PT 195
            |||.|:||||.:..|..|:||::.|:.:|||||....|:....|.|:|:|..:|...:|..  |.
Mouse   132 GNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISHAIEMLLDLIMKRMERCVDKSWIPE 196

  Fly   196 LV---GGGQKGQRLTDQPQGTPNANCNC 220
            .|   .|.....:|:::.:   ...|.|
Mouse   197 GVVRSNGHTSADQLSEEKE---KGLCGC 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	79/174 (45%)
Rab27a	NP_076124.1	Rab27A	6..185	CDD:206700	81/178 (46%)
		Effector region. /evidence=ECO:0000250	38..46		5/7 (71%)