Protein Alignment Rab3 and RAB31

DIOPT Version :10

• Sequence 1: NP_523687.1
• Gene: Rab3 / 36127
• FlyBaseID: FBgn0005586
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_006859.2
• Gene: RAB31 / 11031
• HGNCID: 9771
• Length: 195
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 63/198 - (31%)
• Similarity: 109/198 - (55%)
• Gaps: 11/198 - (5%)

  Fly    23 KLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFRHDKRVKLQIWDTAGQERYRTIT 87
            |:.::|::.|||:|.:.|:..|.|......|:|..|..|||...::..|..|||||||||:.::.
Human     8 KVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLA 72

  Fly    88 TAYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSWDNAQVILVGNKCDMEDQRVISFERGRQL 152
            ..||||:...:::||:|.:|||.:::.||.::|.:..:|..:.:.|||||:.|.|.:..:..::.
Human    73 PMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEY 137

  Fly   153 ADQLGVEFFETSAKENVNVKAVFERLVDIICDKMSESLDADPTLVGGGQKGQRLTDQPQGTPNAN 217
            |:.:|....|||||..:|::.:|:.:     .:....||...    .|..|....::|  |..|:
Human   138 AESIGAIVVETSAKNAINIEELFQGI-----SRQIPPLDPHE----NGNNGTIKVEKP--TMQAS 191

  Fly   218 CNC 220
            ..|
Human   192 RRC 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab3	NP_523687.1	Rab3	21..185	CDD:206657	55/161 (34%)
RAB31	NP_006859.2	Rab5_related	6..168	CDD:206653	55/164 (34%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	30..42		3/11 (27%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	63..79		8/15 (53%)