Protein Alignment CAH13 and CA12

DIOPT Version :10

• Sequence 1: NP_610602.2
• Gene: CAH13 / 36126
• FlyBaseID: FBgn0033542
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001209.1
• Gene: CA12 / 771
• HGNCID: 1371
• Length: 354
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 92/327 - (28%)
• Similarity: 133/327 - (40%)
• Gaps: 66/327 - (20%)

  Fly    60 VLLLIRTPLQFGNTSCSRNSAPVYG----YDMQHGPHTWLPKSRSSSSSVEEATFFQSPVNIDES 120
            ||||:....|      ..:.|||.|    |....|.::|..|..|...      ..|||:::...
Human    11 VLLLVILKEQ------PSSPAPVNGSKWTYFGPDGENSWSKKYPSCGG------LLQSPIDLHSD 63

  Fly   121 QIQRMAIRELLSWNHYDDLPASIT-LENTGQTLILRAQF------HG---NAPT---ISGADLLA 172
            .:|            ||   ||:| ||..|..|....||      |.   |.|:   |.|  |.:
Human    64 ILQ------------YD---ASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQG--LQS 111

  Fly   173 SYTFLELRFHWGWCNS-EGSEHTINHRKFPLEMQVMHKTGSGIPRTCTS---SYDLLMIGYVFEL 233
            .|:..:|..|||..|. .|||||::.:.|..|:.::|......|...|:   |..|.::..:.|:
Human   112 RYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEM 176

  Fly   234 SAHNPFLDPLVQNLRLVQKPGKRVQISPFPISYLMYQFRSGFYSYGGSLTHPPCYQGTEWFIFPE 298
            .:.||..|.:..:|:.|:..|:...:..|.|..|:.:..:.:|.|.||||.|||.....|.:|..
Human   177 GSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRN 241

  Fly   299 SLAISDFQLRHFRLLL---GPDGISP--IARNSRPVQHMGNRVVSLNCFCPYDAAQLSRMHVELC 358
            .:.||..||......|   ..|..||  :..|.|.||....|:|           ..|...|::|
Human   242 PVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLV-----------YTSFSQVQVC 295

  Fly   359 QA 360
            .|
Human   296 TA 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH13	NP_610602.2	alpha_CARP_receptor_like	90..339	CDD:239396	78/270 (29%)
CA12	NP_001209.1	alpha_CA_XII_XIV	39..289	CDD:239400	78/283 (28%)