Protein Alignment CAH13 and CA5A

DIOPT Version :10

• Sequence 1: NP_610602.2
• Gene: CAH13 / 36126
• FlyBaseID: FBgn0033542
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001730.1
• Gene: CA5A / 763
• HGNCID: 1377
• Length: 305
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 79/291 - (27%)
• Similarity: 112/291 - (38%)
• Gaps: 52/291 - (17%)

  Fly    80 APVYGYDMQHGPHTWLPKSRSSSSSVEEATFF--------------QSPVNIDESQIQRMAIREL 130
            ||::...|:  |..|. ..||.:......|..              |||:||
Human    21 APLWSRSMR--PGRWC-SQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINI------------- 69

  Fly   131 LSWNH--YDD--LPASITLE--------NTGQTLILRAQFHGNAPTISGADLLASYTFLELRFHW 183
             .|..  ||.  .|..::.|        |||....:.......|..|||..|...|...:..|||
Human    70 -QWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHW 133

  Fly   184 GWCNSEGSEHTINHRKFPLEMQVMHKTG---SGIPRTCTSSYDLLMIGYVFELSAHNPFLDPLVQ 245
            |..|..|||||::...:|.|:.::|...   ............|.:||...:|.||:..|..||.
Human   134 GAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVD 198

  Fly   246 NLRLVQKPGKRVQISPFPISYLMYQFRSGFYSYGGSLTHPPCYQGTEWFIFPESLAISDFQLRHF 310
            .|..::....|..:.||..|.|:..... :::|.||||.||..:...|.|..|.:.::..||..|
Human   199 ILPEIKHKDARAAMRPFDPSTLLPTCWD-YWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAF 262

  Fly   311 RLL----LGPDGISPIARNSRPVQHMGNRVV 337
            |.|    ||.:. ..:..|.||:|.:.||.|
Human   263 RTLLFSALGEEE-KMMVNNYRPLQPLMNRKV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH13	NP_610602.2	alpha_CARP_receptor_like	90..339	CDD:239396	76/281 (27%)
CA5A	NP_001730.1	alpha_CA_V	61..296	CDD:239392	71/248 (29%)