Protein Alignment CAH13 and CA2

DIOPT Version :10

• Sequence 1: NP_610602.2
• Gene: CAH13 / 36126
• FlyBaseID: FBgn0033542
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_000058.1
• Gene: CA2 / 760
• HGNCID: 1373
• Length: 260
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 67/265 - (25%)
• Similarity: 118/265 - (44%)
• Gaps: 24/265 - (9%)

  Fly    83 YGYDMQHGPHTW---LPKSRSSSSSVEEATFFQSPVNIDESQIQRMAIRELLSWNHYDDLPASIT 144
            :||...:||..|   .|.::...         ||||:||....:.....:.||.::  |...|:.
Human     5 WGYGKHNGPEHWHKDFPIAKGER---------QSPVDIDTHTAKYDPSLKPLSVSY--DQATSLR 58

  Fly   145 LENTGQTLILRAQFHGNAPTISGADLLASYTFLELRFHWGWCNSEGSEHTINHRKFPLEMQVMH- 208
            :.|.|....:......:...:.|..|..:|..::..||||..:.:|||||::.:|:..|:.::|
Human    59 ILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHW 123

  Fly   209 --KTGSGIPRTCTSSYDLLMIGYVFELSAHNPFLDPLVQNLRLVQKPGKRVQISPFPISYLMYQF 271
              |.|. ..:.......|.::|...::.:..|.|..:|..|..::..||....:.|....|:.:
Human   124 NTKYGD-FGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPE- 186

  Fly   272 RSGFYSYGGSLTHPPCYQGTEWFIFPESLAISDFQLRHFRLL-LGPDGISP---IARNSRPVQHM 332
            ...:::|.||||.||..:...|.:..|.:::|..|:..||.| ...:| .|   :..|.||.|.:
Human   187 SLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEG-EPEELMVDNWRPAQPL 250

  Fly   333 GNRVV 337
            .||.:
Human   251 KNRQI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH13	NP_610602.2	alpha_CARP_receptor_like	90..339	CDD:239396	65/258 (25%)
CA2	NP_000058.1	alpha_CA_I_II_III_XIII	1..259	CDD:239393	67/265 (25%)