Protein Alignment CAH13 and CA1

DIOPT Version :10

• Sequence 1: NP_610602.2
• Gene: CAH13 / 36126
• FlyBaseID: FBgn0033542
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001729.1
• Gene: CA1 / 759
• HGNCID: 1368
• Length: 261
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 81/271 - (29%)
• Similarity: 133/271 - (49%)
• Gaps: 27/271 - (9%)

  Fly    79 SAPVYGYDMQHGPHTW---LPKSRSSSSSVEEATFFQSPVNIDESQIQR-MAIREL-LSWNHYDD 138
            ::|.:|||.::||..|   .|.:..::         ||||:|..|:.:. .:::.: :|:|
Human     2 ASPDWGYDDKNGPEQWSKLYPIANGNN---------QSPVDIKTSETKHDTSLKPISVSYN---- 53

  Fly   139 LPASI-TLENTGQTLILRAQFHGNAPTISGADLLASYTFLELRFHWGWCNSEGSEHTINHRKFPL 202
             ||:. .:.|.|.:..:..:.:.|...:.|.....||...:..||||..|..|||||::..|:..
Human    54 -PATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSA 117

  Fly   203 EMQVMHKTG---SGIPRTCTSSYDLLMIGYVFELSAHNPFLDPLVQNLRLVQKPGKRVQISPFPI 264
            |:.|.|...   |.:....:.:..|.:||.:.::...||.|..::..|:.::..|||...:.|..
Human   118 ELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDP 182

  Fly   265 SYLMYQFRSGFYSYGGSLTHPPCYQGTEWFIFPESLAISDFQLRHFRLLLG---PDGISPIARNS 326
            |.|: .....|::|.|||||||.|:...|.|..||:::|..||..||.||.   .|...|:..|:
Human   183 STLL-PSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNN 246

  Fly   327 RPVQHMGNRVV 337
            ||.|.:..|.|
Human   247 RPTQPLKGRTV 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH13	NP_610602.2	alpha_CARP_receptor_like	90..339	CDD:239396	77/260 (30%)
CA1	NP_001729.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		9/37 (24%)
		alpha_CA	2..261	CDD:469577	81/271 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..261		7/17 (41%)