Protein Alignment CAH13 and CA14

DIOPT Version :10

• Sequence 1: NP_610602.2
• Gene: CAH13 / 36126
• FlyBaseID: FBgn0033542
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_036245.1
• Gene: CA14 / 23632
• HGNCID: 1372
• Length: 337
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 72/283 - (25%)
• Similarity: 111/283 - (39%)
• Gaps: 62/283 - (21%)

  Fly    85 YDMQHGPHTWLPKSRSSSSSVEEATFFQSPVNIDESQIQRMAIRELLSWNHYD-DLPA------- 141
            |:..||...|      .:|..|.....|||::|....:.            :| ||||
Human    24 YEGPHGQDHW------PASYPECGNNAQSPIDIQTDSVT------------FDPDLPALQPHGYD 70

  Fly   142 -----SITLENTGQTLILRAQFHGNAP-TISGADLLASYTFLELRFHWGWCNSE-GSEHTINHRK 199
                 .:.|.|.|.|:.|      :.| |:....|...|...:|..|||...|. ||||.||...
Human    71 QPGTEPLDLHNNGHTVQL------SLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEA 129

  Fly   200 FPLEMQVMHKTGSGIPRTCTSSYD-----------LLMIGYVFEL-SAHNPFLDPLVQNLRLVQK 252
            ...|:.::|..        :.|||           |.::|.:.|: ...|...:.::.:|..|:.
Human   130 TFAELHIVHYD--------SDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRH 186

  Fly   253 PGKRVQISPFPISYLMYQFRSGFYSYGGSLTHPPCYQGTEWFIFPESLAISDFQLRHFRLLLGPD 317
            ..::..:.||.:..|:.:....::.|.||||.|||||...|.:|.....||..||...:..|...
Human   187 KDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFST 251

  Fly   318 GISP---IARNSRPVQHMGNRVV 337
            ...|   :.:|.|.:|.:..|:|
Human   252 EEEPSKLLVQNYRALQPLNQRMV 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH13	NP_610602.2	alpha_CARP_receptor_like	90..339	CDD:239396	70/278 (25%)
CA14	NP_036245.1	alpha_CA_XII_XIV	29..278	CDD:239400	70/278 (25%)