DRSC/TRiP Functional Genomics Resources

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Protein Alignment Elp2 and Ciao1

DIOPT Version :9

Sequence 1:NP_610600.1 Gene:Elp2 / 36123 FlyBaseID:FBgn0033540 Length:794 Species:Drosophila melanogaster
Sequence 2:NP_079572.2 Gene:Ciao1 / 26371 MGIID:1346998 Length:339 Species:Mus musculus


Alignment Length:237 Identity:69/237 - (29%)
Similarity:104/237 - (43%) Gaps:49/237 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   565 LAATADGSLLASTCKASNAEHAQIILWNP--SNWKQIQKLS-GHQLTVTQLSFSPDSRYLLSVSR 626
            ||....|:|||| |....    :|.:|..  .:|.....|| |||.||.::::||...||.|.|.
Mouse    22 LAWNPSGTLLAS-CGGDR----KIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

  Fly   627 DRRWCLYER-QDSSVSYQLVASTDKSNGVHTRIIWSCDWSHDGQFFVTSSRDGKVVVWKKEEDCK 690
            |...|:::: ||   .::.|.:.:.    |...:.|..|:..|....|.|||..|.||:.:|:  
Mouse    82 DATTCIWKKNQD---DFECVTTLEG----HENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEE-- 137

  Fly   691 ESSLNGWQANGVLELKNESITAVAF--------SNSYLSGTDDTYILALGTETGLIKIYQFVRGA 747
                :.::...||....:.:..|.:        |.||    |||           :|:||.....
Mouse   138 ----DEYECVSVLSSHTQDVKHVVWHPSQELLASASY----DDT-----------VKLYQEEGDD 183

  Fly   748 WKLLSDLNKSQAHHLTVRRLQFRPGKQLQLASCGEDHLVRIY 789
            |...:.|   :.|..||..:.|.|..| :||||.:|..|||:
Mouse   184 WVCCATL---EGHESTVWSIAFDPSGQ-RLASCSDDRTVRIW 221

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Elp2NP_610600.1 WD40 <2..236 CDD:225201
WD40 repeat 18..55 CDD:293791
WD40 50..412 CDD:295369
WD40 repeat 104..145 CDD:293791
WD40 repeat 150..202 CDD:293791
WD40 repeat 209..281 CDD:293791
WD40 237..741 CDD:225201 51/187 (27%)
WD40 repeat 291..331 CDD:293791
WD40 repeat 337..382 CDD:293791
WD40 repeat 389..412 CDD:293791
WD40 552..790 CDD:295369 69/237 (29%)
WD40 repeat 563..604 CDD:293791 13/41 (32%)
WD40 repeat 609..652 CDD:293791 12/43 (28%)
WD40 repeat 660..695 CDD:293791 11/34 (32%)
WD40 repeat 702..758 CDD:293791 14/63 (22%)
WD40 repeat 764..791 CDD:293791 12/26 (46%)
Ciao1NP_079572.2 WD 1 14..53 11/35 (31%)
WD40 17..332 CDD:238121 69/237 (29%)
WD40 repeat 19..58 CDD:293791 12/40 (30%)
WD 2 59..98 15/41 (37%)
WD40 repeat 65..103 CDD:293791 11/40 (28%)
WD 3 103..142 12/48 (25%)
WD40 repeat 108..147 CDD:293791 12/44 (27%)
WD 4 148..187 11/53 (21%)
WD40 repeat 154..191 CDD:293791 12/54 (22%)
LYR motif, required for interaction with HSC20. /evidence=ECO:0000250|UniProtKB:O76071 176..178 0/1 (0%)
WD 5 192..231 14/31 (45%)
WD40 repeat 197..248 CDD:293791 12/26 (46%)
WD 6 250..289
WD40 repeat 255..295 CDD:293791
WD 7 301..339
WD40 repeat 306..331 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0645
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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