Protein Alignment Elp2 and Elp2

DIOPT Version :10

• Sequence 1: NP_610600.1
• Gene: Elp2 / 36123
• FlyBaseID: FBgn0033540
• Length: 794
• Species: Drosophila melanogaster
• Sequence 2: XP_308870.5
• Gene: Elp2 / 1270192
• VectorBaseID: AGAMI1_003974
• Length: 794
• Species: Anopheles gambiae
• Alignment Length: 811
• Identity: 428/811 - (52%)
• Similarity: 571/811 - (70%)
• Gaps: 35/811 - (4%)

  Fly     1 MQVENLHTSVACNRCTECADWGPNGWIAYGACNAIAIMDPKFQGNSAKVLFTLVEHTKRVNTVRW 65
            |.||.::||.||||..:..||||:|.|.:.|.||||:.|||:.| |.|::.||:.|..||||||.
Mosquito     1 MFVETIYTSAACNRTPDSLDWGPDGLIYFAANNAIAVFDPKYHG-SVKIVRTLIGHKARVNTVRV 64

  Fly    66 L----DCD---KLLSGGDDAIAILWELDETGTTKSFTLKGHTSGVNTVDG-IRQQDGSWLLATAA 122
            :    :|.   .||||.||...|||...:.|....|.|||||.||..||. :.....:.::||.:
Mosquito    65 VRDGSECHGGINLLSGSDDGTCILWNTKQDGGAVRFILKGHTKGVTAVDALVDTATNNLIVATGS 129

  Fly   123 ADTTIKLW-TFQDNNYVCFQTISLSDGFCFCLRLQLLPKSNQVLLAFSGDDETVSLWSEQVETAG 186
            .|::|||| ...::.:.|.|||.|..|..|.::|..||:||.|:||::.|.:.|.|...|..|
Mosquito   130 VDSSIKLWQATAESTFECTQTIDLRSGLTFAMKLFCLPRSNAVMLAYTTDTDVVKLCVRQKRT-- 192

  Fly   187 EGDSLGRQFQRKHKLTGHEDWVRGLDFV--VDGEDLLLASGSQDNFIRLWRIAPRSKEQMQENRV 249
              |:....|:...:|.||.|||||||.:  .|.||.||||.|||.|||||||:||:..|.|:...
Mosquito   193 --DADEATFEPVEQLKGHCDWVRGLDCIQLPDSEDWLLASSSQDTFIRLWRISPRASLQKQKEFK 255

  Fly   250 DLHQLSHNDDEIKVEEKILQL----GKEAWYAVSLESVLYGHEGWIYGVHWHKTPDQELRLLSAS 310
            ::..    :::|.:||:...:    |....||:||||||.|||||:||||:... |.:|.|||:|
Mosquito   256 EILL----EEDITLEERTFTVRAADGAAYHYALSLESVLQGHEGWVYGVHFCMR-DGKLHLLSSS 315

  Fly   311 IDKTVIIWAPTEEGIWLEEVRVGEVGGNSVGFYGGKFSGDGHSIMAHSYQGGFHIWSQDPDRPQL 375
            |||::.:|.|:|.|:|:|.||||||||:|:||||||||.||.||:.|.:||.||:|.:|.::|.|
Mosquito   316 IDKSLTVWTPSESGVWVESVRVGEVGGSSLGFYGGKFSPDGSSIIGHGFQGSFHLWREDAEQPGL 380

  Fly   376 WTPGVIVGGHYGEVRDLAWEHSGA-YLMTASADQTTRLHAPWLQDGANPTWHELARPQIHGYDMQ 439
            |.||.|:|||:|.||||||:.:|. |::|.|||||||:||||.:.....|||||.|||:||||||
Mosquito   381 WKPGTILGGHFGGVRDLAWDPAGGMYVVTLSADQTTRIHAPWSRPEGEETWHELGRPQVHGYDMQ 445

  Fly   440 ALALLSRYKFASGAEEKIVRTFQAPANFIENFRHISGIENDDAGDVLLDSLPKGASVPSLGLSNK 504
            .|.|||||:.||.|||||:|.||||:||::|||.:.|:..|..||.:::|.|.||||||||||||
Mosquito   446 CLTLLSRYRLASAAEEKIIRIFQAPSNFVQNFRALCGVVTDPEGDAVVESNPMGASVPSLGLSNK 510

  Fly   505 AVYKVDSEVESTSKTSKDEYPDNYFVPIALETPPQEETLMQNTLWPELQKLYGHGYEIFALAATA 569
            ||::|::. |:.|:..||.||::||.|||||:||.||||||||||||:|||||||.|::|:.::.
Mosquito   511 AVFEVETP-ETDSRHIKDMYPEHYFSPIALESPPAEETLMQNTLWPEIQKLYGHGNELYAIVSSP 574

  Fly   570 DGSLLASTCKASNAEHAQIILWNPSNWKQIQKLSGHQLTVTQLSFSPDSRYLLSVSRDRRWCLYE 634
            ||:|:||.|:|::.:.|||:||:.::|:.:|:|:.||||||||:|:||.:|||||||||.:.::.
Mosquito   575 DGALIASGCRATSTDQAQILLWDTASWRVVQQLTAHQLTVTQLAFAPDGQYLLSVSRDRTFSVFR 639

  Fly   635 RQDSSVSYQLVASTDKSNGVHTRIIWSCDWSHDGQFFVTSSRDGKVVVWK-KEEDCKESSLNGWQ 698
            |..|  :::||..:||:.||||||||.||||||.:.|.|.|||||||.|| ..|:...:::..::
Mosquito   640 RVSS--AFELVMRSDKTKGVHTRIIWCCDWSHDSKRFATGSRDGKVVAWKASNEESNGAAVAPFE 702

  Fly   699 ANGVLELKNESITAVAFSNSYLSGTDDTYILALGTETGLIKIYQFVRGAWKLLSDLNKSQAHHLT 763
            ..|||||||||||||||....||  |..|::|:|.|:|:||:|..  |.|.||.::::..|||||
Mosquito   703 QAGVLELKNESITAVAFGRRKLS--DGRYLVAVGLESGVIKLYAL--GQWDLLLNISEDHAHHLT 763

  Fly   764 VRRLQFRPG-KQLQLASCGEDHLVRIYDIKL 793
            |:||.|||. :|.||||||||.|||:|.|||
Mosquito   764 VKRLSFRPHVEQHQLASCGEDGLVRVYSIKL 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Elp2	NP_610600.1	WD40 repeat	18..55	CDD:293791	19/36 (53%)
		WD40	50..412	CDD:475233	179/377 (47%)
		WD40 repeat	104..145	CDD:293791	13/42 (31%)
		WD40 repeat	150..202	CDD:293791	16/51 (31%)
		WD40 repeat	209..281	CDD:293791	32/77 (42%)
		WD40 repeat	291..331	CDD:293791	19/39 (49%)
		WD40 repeat	337..382	CDD:293791	26/44 (59%)
		WD40 repeat	389..412	CDD:293791	15/23 (65%)
		WD40	<548..792	CDD:441893	134/245 (55%)
		WD40 repeat	563..604	CDD:293791	16/40 (40%)
		WD40 repeat	609..652	CDD:293791	22/42 (52%)
		WD40 repeat	660..695	CDD:293791	19/35 (54%)
		WD40 repeat	702..758	CDD:293791	29/55 (53%)
		WD40 repeat	764..791	CDD:293791	19/27 (70%)
Elp2	XP_308870.5	None