Protein Alignment Git and GLO3

DIOPT Version :9

• Sequence 1: NP_610599.3
• Gene: Git / 36122
• FlyBaseID: FBgn0033539
• Length: 731
• Species: Drosophila melanogaster
• Sequence 2: NP_011048.1
• Gene: GLO3 / 856859
• SGDID: S000000924
• Length: 493
• Species: Saccharomyces cerevisiae
• Alignment Length: 627
• Identity: 117/627 - (18%)
• Similarity: 204/627 - (32%)
• Gaps: 207/627 - (33%)

  Fly    42 SRLQTEVCGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKSLRQGNWEPSVLNFVNSLN 106
            |.::..||.|||..:|:|.|:..|::||..|.:|||::|.||:.|||.....|.      :|:|.
Yeast    24 SNMENRVCFDCGNKNPTWTSVPFGVMLCIQCSAVHRNMGVHITFVKSSTLDKWT------INNLR 82

  Fly   107 AHGANSVWEHHLLDGSTNSTGGKHVPRWRKPTPKDALHPTKSDFIKAKHVNLTFVLKPSLQDDDD 171
            ..                ..||.|..|                         .|.||
Yeast    83 RF----------------KLGGNHKAR-------------------------DFFLK-------- 98

  Fly   172 GNGSAGCLEQELSRQLHASVRTSNLETSLRFLVQGADPNYYHEDKLSTPLHMAAKFGQASQIEML 236
            .||          :||   :.|:|::...::....|.....|.||      ...|..:....|::
Yeast    99 NNG----------KQL---LNTANVDAKTKYTSPVAKKYKIHLDK------KVQKDMELYPSELV 144

  Fly   237 LIYGADVNALDGNGMTPLELARANNHNTIAERLLDAMY--------DVTDRIITFLGGKKP-DHA 292
            |      |..|.:. :||:.....:.:|..|..:|..:        :.:.::....|...| ::.
Yeast   145 L------NGQDSSD-SPLDTDSDASRSTSKENSVDDFFSNWQKPSSNSSSKLNVNTGSLAPKNNT 202

  Fly   293 SG----------RHMII------PDANGADISEQ--LKIARGKLQLVPNKMFEELVMDLYDEVDR 339
            :|          |..|:      |..|..|..:.  |..:|...:|...|:.:....||:|:. :
Yeast   203 TGSTPKTTVTKTRSSILTASRKKPVLNSQDKKKHSILSSSRKPTRLTAKKVDKSQAEDLFDQF-K 266

  Fly   340 RECEAIWSTSTLNADHATVPFLPAN----PFLSATRNQGRQKLARFNRA--EFTGLLTDV--LVD 396
            :|.:........|:..:|.  :..|    .|::.::......:...|..  ||...|.|.  ..|
Yeast   267 KEAQQEKEDEFTNSSSSTK--IRQNDYDSQFMNNSKGNNNNSIDDINTQPDEFNDFLNDTSNSFD 329

  Fly   397 AMRRQNMANLRPMDAPVAGHQSLQSLPYANNSMLLGSFEQGGHDPNLSDDEPIYDPVASDDDYAP 461
            ..|::....|.|                        .|.:.|....::|          .:|.|.
Yeast   330 TTRKEQQDTLTP------------------------KFAKLGFGMTMND----------ANDLAK 360

  Fly   462 VPPMAQQAIVHTPPRSANSHNEMETLRKQLNDYKSEINQLKNVVQMLSSENTQLKSKFSSASNNS 526
            ....:|:  :...||                 |...|.:.....:.:||:....:..|..|:|..
Yeast   361 QQKESQK--IAQGPR-----------------YTGRIAERYGTQKAISSDQLFGRGSFDEAANRE 406

  Fly   527 VYDEPLRID--LSLSSPDTEHEPLSLPEGGTANGESGSSNDSSNQSTIKRPASMYERRLVPNVAK 589
            .:|:....|  .|:||.....|...:.|.|.....|||                         ..
Yeast   407 AHDKLKTFDNATSISSSSYFGEDKEVDEFGNPINSSGS-------------------------GA 446

  Fly   590 GNTDIRNTTS---MYQMAGDGKPFGEEVKVRSDLVTRRLKEL 628
            ||.|.||:.:   .:..:.|     :|:::..|:|.:..::|
Yeast   447 GNFDGRNSNNGFIDFNASAD-----DELQMLRDVVEQGAEKL 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Git	NP_610599.3	ArfGap	48..164	CDD:279720	30/115 (26%)
		Ank_2	187..279	CDD:289560	17/99 (17%)
		ANK	<187..270	CDD:238125	16/82 (20%)
		ANK repeat	187..213	CDD:293786	4/25 (16%)
		ANK repeat	215..247	CDD:293786	6/31 (19%)
		ANK repeat	249..279	CDD:293786	5/37 (14%)
		GIT_SHD	314..342	CDD:285690	6/27 (22%)
		GIT	374..404	CDD:128828	7/33 (21%)
		GIT1_C	609..727	CDD:289013	4/20 (20%)
GLO3	NP_011048.1	COG5347	9..363	CDD:227651	86/456 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900