DRSC/TRiP Functional Genomics Resources

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Protein Alignment Git and AGE2

DIOPT Version :9

Sequence 1:NP_610599.3 Gene:Git / 36122 FlyBaseID:FBgn0033539 Length:731 Species:Drosophila melanogaster
Sequence 2:NP_012220.3 Gene:AGE2 / 854767 SGDID:S000001306 Length:298 Species:Saccharomyces cerevisiae


Alignment Length:254 Identity:66/254 - (25%)
Similarity:96/254 - (37%) Gaps:46/254 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 SDPATPTISTRSKMPRGKSRLQTEVCGDCGAG-DPSWASINRGILLCADCCSVHRSLGRHISIVK 87
            |.|....:|...:.| |.|.     |.||.|. .|.|||.:.|:.:|..|..:|||||.|||.||
Yeast     4 SVPVKKALSALLRDP-GNSH-----CADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVK 62

  Fly    88 SLRQGNWEP----SVLNFVNSLNAHGANSVWEHHLLDGSTNSTGGKHVPRWRKPTPKDALHPTKS 148
            |:....|:.    .::.|.|:|.   |||.:|..|.|..          :.||.|...:|    .
Yeast    63 SVDLDTWKEEHLVKLIQFKNNLR---ANSYYEATLADEL----------KQRKITDTSSL----Q 110

  Fly   149 DFIKAKHVNLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASVRTSNLETSLRFLVQGADPNYYH 213
            :|||.|     :..|..:.|.....|    |.......||......:|..|...|.|.:  |...
Yeast   111 NFIKNK-----YEYKKWIGDLSSIEG----LNDSTEPVLHKPSANHSLPASNARLDQSS--NSLQ 164

  Fly   214 EDKLSTPLHMAAKFGQASQIEMLLIYGADVNALDGN-----GMTPLELARANNHNTIAE 267
            :.:...|.|:.:.  ..|...:|.:..:.::....|     ..|.:..|.....|.:.|
Yeast   165 KTQTQPPSHLLST--SRSNTSLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGNRVGE 221

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GitNP_610599.3 ArfGap 48..164 CDD:279720 40/120 (33%)
Ank_2 187..279 CDD:289560 16/86 (19%)
ANK <187..270 CDD:238125 16/86 (19%)
ANK repeat 187..213 CDD:293786 7/25 (28%)
ANK repeat 215..247 CDD:293786 4/31 (13%)
ANK repeat 249..279 CDD:293786 5/24 (21%)
GIT_SHD 314..342 CDD:285690
GIT 374..404 CDD:128828
GIT1_C 609..727 CDD:289013
AGE2NP_012220.3 COG5347 1..298 CDD:227651 66/254 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5347
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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