DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Git and AGD1

DIOPT Version :9

Sequence 1:	NP_610599.3	Gene:	Git / 36122	FlyBaseID:	FBgn0033539	Length:	731	Species:	Drosophila melanogaster
Sequence 2:	NP_201004.2	Gene:	AGD1 / 836319	AraportID:	AT5G61980	Length:	828	Species:	Arabidopsis thaliana

Alignment Length:	327	Identity:	93/327 - (28%)
Similarity:	134/327 - (40%)	Gaps:	69/327 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LQTEVCGDCGAGDPSWASINRGILLCADCCSVHRSLGRHISIVKSLRQG--NWEPSVLNFVNSLN 106
            |..|.|.||||.:|.|||:|.|:|:|.:|..:||:||.|||.|:||...  .||||||....||.
plant   508 LGNERCADCGAPEPDWASLNLGVLICIECSGIHRNLGVHISKVRSLTLDVKVWEPSVLTLFQSLG 572

  Fly   107 AHGANSVWEHHLLDGSTNSTGGKHV-------PR---WRKPTPKDALHPTKSDFIKAKHVNLTFV 161
            ....|||||..|...|..|:..:..       ||   .|||...|.: ..|..||.||:....||
plant   573 NVYVNSVWEELLNSESRTSSASRSSGTPKSDRPRKLLVRKPGFNDPI-SVKELFIHAKYSERIFV 636

  Fly   162 LK---------------PSLQDDD-------------DGNGSAGCLEQELSRQLHASVR-TSNLE 197
            .|               .:::.:|             |.|...|.....:|..|...:: ...||
plant   637 RKAIDSQHFQAVFQEIWENVRANDKKSVYRHIVCSEADVNALRGQASYTVSLPLSKMMQMEETLE 701

  Fly   198 TSLRFLVQ-------------GADPNYYHEDKLS--TPLHMAAKFGQASQIEMLLIYGADVNALD 247
            ...:.:.:             |...:...|:..:  :.||:|........:|:||.|||.:||.|
plant   702 AKFKSIEEEFQENPAGYSNSRGDGESMVREETSNDCSLLHLACLSADIGMVELLLQYGAKINATD 766

  Fly   248 GNGMTPLELARANNHNTIAERLLDAMYDVTDRIITFLGGKKPDHASGRHMIIPDANGADISEQLK 312
            ..|.|||      :|..|:.|...|      |::...||.........::.:..|:..|:::...
plant   767 SKGRTPL------HHCIISRRYAIA------RLLLMRGGDPNAVDKDSNIPVKYASQTDLNDSEL 819

  Fly   313 IA 314
            ||
plant   820 IA 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Git	NP_610599.3	ArfGap	48..164	CDD:279720	54/142 (38%)
		Ank_2	187..279	CDD:289560	25/107 (23%)
		ANK	<187..270	CDD:238125	24/98 (24%)
		ANK repeat	187..213	CDD:293786	4/39 (10%)
		ANK repeat	215..247	CDD:293786	11/33 (33%)
		ANK repeat	249..279	CDD:293786	8/29 (28%)
		GIT_SHD	314..342	CDD:285690	1/1 (100%)
		GIT	374..404	CDD:128828
		GIT1_C	609..727	CDD:289013
AGD1	NP_201004.2	BAR_SFC_plant	15..215	CDD:153290
		PH	289..425	CDD:278594
		PH_ACAP	291..429	CDD:270070
		ArfGap	498..639	CDD:279720	55/131 (42%)
		ANK	734..>826	CDD:238125	27/100 (27%)
		Ank_4	738..789	CDD:290365	21/62 (34%)
		ANK repeat	740..766	CDD:293786	11/25 (44%)
		ANK repeat	768..799	CDD:293786	11/42 (26%)
		Ank_4	769..823	CDD:290365	15/65 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810