DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Git and SFC

DIOPT Version :9

Sequence 1:	NP_610599.3	Gene:	Git / 36122	FlyBaseID:	FBgn0033539	Length:	731	Species:	Drosophila melanogaster
Sequence 2:	NP_196834.3	Gene:	SFC / 831171	AraportID:	AT5G13300	Length:	827	Species:	Arabidopsis thaliana

Alignment Length:	321	Identity:	93/321 - (28%)
Similarity:	137/321 - (42%)	Gaps:	90/321 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LDHSDPATPTISTRSKMPRGKSRLQT--EVCG-----DCGAGDPSWASINRGILLCADCCSVHRS 78
            |.:::..:.:...:..:.:|:..:..  :|||     ||||.:|.|||:|.|:|:|.:|..|||:
plant   481 LGYNERPSRSFQPQRSIRKGEKPIDALRKVCGNDKCADCGAPEPDWASLNLGVLVCIECSGVHRN 545

  Fly    79 LGRHISIVKSLRQG--NWEPSVLNFVNSLNAHGANSVWEH--------HLLDGSTNS-------T 126
            ||.|||.|:||...  .|||||::...:|....||:|||.        |...|.|.|       |
plant   546 LGVHISKVRSLTLDVKVWEPSVISLFQALGNTFANTVWEELLHSRSAIHFDPGLTVSDKSRVMVT 610

  Fly   127 GGKHVPRWRKPTPKDALHPTKSDFIKAKHVNLTFVLKPSLQDDDDGNGSAGCLEQELSRQLHASV 191
            |        ||:..|.: ..|..:|:||:....||.:.  :|.|        ..|..::|:..:|
plant   611 G--------KPSYADMI-SIKEKYIQAKYAEKLFVRRS--RDSD--------FPQSAAQQMWDAV 656

  Fly   192 RTSNLETSLRFLVQG-ADPNYYH----------------------EDKL---------------- 217
            ..::.:...|.:|.| ||.||.:                      ||.|
plant   657 SGNDKKAVYRLIVNGDADVNYVYDQTSSSSLTLSRVILVPERPKREDVLLRLRNELLDRTGSSSN 721

  Fly   218 --------STPLHMAAKFGQASQIEMLLIYGADVNALDGNGMTPLELARANNHNTIAERLL 270
                    |:.||.|.:......:|:||.|||:|||.|.:|.|||.........|||..||
plant   722 ISPEGSGGSSLLHCACEKADLGMVELLLQYGANVNASDSSGQTPLHCCLLRGKVTIARLLL 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Git	NP_610599.3	ArfGap	48..164	CDD:279720	53/137 (39%)
		Ank_2	187..279	CDD:289560	34/131 (26%)
		ANK	<187..270	CDD:238125	32/129 (25%)
		ANK repeat	187..213	CDD:293786	8/26 (31%)
		ANK repeat	215..247	CDD:293786	15/55 (27%)
		ANK repeat	249..279	CDD:293786	9/22 (41%)
		GIT_SHD	314..342	CDD:285690
		GIT	374..404	CDD:128828
		GIT1_C	609..727	CDD:289013
SFC	NP_196834.3	BAR_SFC_plant	14..215	CDD:153290
		PH	293..430	CDD:278594
		PH_ACAP	295..434	CDD:270070
		ArfGap	501..639	CDD:279720	53/146 (36%)
		ANK	711..816	CDD:238125	23/72 (32%)
		Ank_4	729..782	CDD:290365	21/52 (40%)
		ANK repeat	729..759	CDD:293786	13/29 (45%)
		ANK repeat	761..792	CDD:293786	9/22 (41%)
		Ank_4	764..816	CDD:290365	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5347
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810